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Latest recombination Stories

2010-11-04 13:51:17

The autoimmune disease type 1 diabetes (T1D), also known as juvenile diabetes, is diagnosed in approximately 70,000 children worldwide per year. Genetics is increasingly being recognized as playing a significant role in susceptibility to the disorder, but outside a handful of genes, a clear understanding of the genetic architecture that underlies T1D has remained elusive. In a study published online today in Genome Research (www.genome.org), scientists have identified a novel gene associated...

2010-10-27 12:25:00

REYKJAVIK, Iceland, October 27, 2010 /PRNewswire-FirstCall/ -- Scientists from deCODE genetics today publish in Nature the highest resolution recombination map of the human genome yet developed. Recombination is the reshuffling of the genome that occurs in the formation of eggs and sperm: we inherit one version of each chromosome from each of our parents, and create novel blends of the two that we pass on to our offspring. This process is fundamental to generating human diversity,...

2010-08-12 15:05:00

Molecular connection is crucial to fix DNA double-strand breaks A team of investigators led by a physician-scientist at The University of Texas MD Anderson Cancer Center has shown for the first time that the small protein SUMO can team up with the replication protein A (RPA) complex to facilitate DNA repair. The study is published in the Aug. 13 edition of the journal Molecular Cell. RPA 70 is a component of multiprotein machinery called the RPA complex, which plays a crucial role in DNA...

2009-12-07 05:51:00

VIENNA, Austria, December 7 /PRNewswire/ -- EUCODIS Bioscience, a company developing, customizing, manufacturing, and marketing enzymes for the chemical industry, announced today that it has appointed Mr Thomas Fischer, currently CFO, as new CEO of the Company. Going forward, EUCODIS Bioscience' sole focus will be to provide high-performance enzymes to customers, capitalizing on the Company's experience in commercial enzyme development and on its proven technology of "in vivo...

2009-12-04 15:08:06

A protein that plays a key role in copying DNA also plays a vital role in repairing breaks in it, UC Davis scientists have found. The work is helping researchers understand how cancer cells can resist radiation and chemotherapy, as well as how cells become cancerous in the first place. The protein, known as proliferating cell nuclear antigen, forms a ring that fits around the DNA double helix. This cuff-like ring helps to keep in place DNA polymerase, the enzyme that makes a copy of the DNA...

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2009-11-14 07:49:18

Meiosis "“ the pairing and recombination of chromosomes, followed by segregation of half to each egg or sperm cell "“ is a major crossroads in all organisms reproducing sexually. Yet, how the cell precisely choreographs these chromosomal interactions is a long-standing question. New findings by University of California, Berkeley, scientists show that the cell's cytoskeleton, which moves things around in the cell, plays a critical role, essentially reaching into the nucleus to...

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2009-10-21 11:47:59

Researchers report that a single-stranded DNA-binding protein (SSB), once thought to be a static player among the many molecules that interact with DNA, actually moves back and forth along single-stranded DNA, gradually allowing other proteins to repair, recombine or replicate the strands. Their study, of SSB in the bacterium Escherichia coli, appears today in the journal Nature. Whenever the double helix of DNA unravels, exposing each strand to the harsh environment of the cell, SSB is...

2009-09-03 15:25:35

The unique mechanism behind the evolutionary survival of the human Y chromosome may also be responsible for a range of sex disorders, from failed sperm production to sex reversal to Turner Syndrome. Roughly six years ago, David Page's lab at Whitehead Institute for Biomedical Research reported the discovery of eight large areas of mirror-imaged genetic sequences, or palindromes, along the Y chromosome. Because the Y chromosome essentially has no partner with which to swap genes, a process...

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2009-08-05 09:20:00

As the body creates antibodies to fight invaders, a three-protein DNA repair complex called MRN is crucial for a normal gene-shuffling process to proceed properly, University of Michigan research shows.The discoveries in mice, published online this week in Nature Structural and Molecular Biology, advance understanding of the immune system and shed light on how B-cell lymphoma and some other cancers may begin.U-M scientists found that:When one protein in the MRN complex, Mre11, is absent,...

2009-07-20 13:52:51

Research led by scientists at Iowa State University's Plant Sciences Institute has resulted in a process that will make genetic changes in plant genes much more efficient, practical and safe. The breakthrough was developed by David Wright, an associate scientist, and Jeffery Townsend, an assistant scientist, and allows targeted genetic manipulations in plant DNA, which could have a huge impact on plant genetic work in the future. Until now, when scientists introduced DNA into plants, they...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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