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Latest Red blood cell Stories

2010-08-17 17:42:38

A UCSF-led team has discovered at least one key reason why blood stem cells are susceptible to developing the genetic mutations that can lead to adult leukemia. Their finding also may explain, they say, why some other age-related hematological disorders develop. The study, reported in "Cell Stem Cell" (Aug. 6, 2010) and reviewed in Cell Stem Cell and Cell, opens a new frontier for studying the molecular underpinnings of adult leukemia. The discovery also suggests a possible therapeutic...

2010-08-05 14:08:10

Finding is important for diagnosis and treatment of cancer and anemia Hematopoietic stem cells provide the body with a constant supply of blood cells, including the red blood cells that deliver oxygen and the white blood cells that make up the immune system. Hematopoietic"”or blood"”stem cells must also make more copies of themselves to ensure that they are present in adequate numbers to provide blood throughout a person's lifetime, which means they need to strike a delicate...

2010-08-04 16:29:17

EMBL scientists identify proteins that ensure iron balance Most organisms need iron to survive, but too much iron is toxic, and can cause fatal organ failure. The same is true inside cells, where iron balance must also be maintained. In a study published today in Cell Metabolism, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered that a group of proteins named IRPs ensure that this iron balance is kept and as such are essential for cell...

2010-08-02 16:16:28

Genetic molecules resist chemical stress, may have wider roles Pediatric researchers have discovered a new biological pathway in which small segments of RNA, called microRNA, help protect red blood cells from injury caused by chemicals called free radicals. The microRNA seems to have only a modest role when red blood cells experience normal conditions, but steps into action when the cells are threatened by oxidant stress. Led by hematologist Mitchell Weiss, M.D., Ph.D., of The Children's...

2010-08-02 16:11:24

Researchers at UT Southwestern Medical Center have uncovered a key step in the creation of new red blood cells in an animal study. They found that a tiny fragment of ribonucleic acid (RNA), a chemical cousin of DNA, prompts stem cells to mature into red blood cells. The researchers also created an artificial RNA inhibitor to block this process. Such interventions, if fruitful in humans, might be useful against some cancers and other diseases, such as polycythemia vera, in which the body...

2010-07-12 13:53:49

A retired but well-preserved mechanism for regulating viruses that has worked its way into the human genome appears to modulate a switch between adult and fetal hemoglobin production, Medical College of Georgia researchers report. That switch could be the key to more targeted therapies for sickle cell patients whose misshaped adult hemoglobin hinders its ability to deliver oxygen throughout the body. Fetal hemoglobin, on the other hand, can't take on the dysfunctional sickle shape. After...

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2010-07-11 07:25:00

American scientists have developed "artificial blood" that could soon be used to treat soldiers who are wounded during battle. The artificial blood is created by taking cells from umbilical cords and using a machine to imitate the way bone marrow works to produce mass quantities of usable units of red blood cells. Producing the genetically-engineered blood is known as "Ëœblood pharming'. The program was launched in 2008 by the Pentagon's experimental sector, Darpa, to find a way...

2010-07-08 14:59:11

Genetic mechanism once thought rare may allow rapid cell production We take our blood for granted, but its creation requires a complicated series of steps, starting with the formation of blood stem cells during early embryonic development, followed by progressive differentiation into the progenitors of red cells, white cells and platelets, and ultimately the full set of blood cells. Now, in the July 9 issue of Cell, researchers at Children's Hospital Boston report a surprising twist in how...

2010-07-02 19:20:15

Cells from frozen human blood samples can be reprogrammed to an embryonic stem-cell-like state, according to Whitehead Institute researchers. These cells can be multiplied and used to study the genetic and molecular mechanisms of blood disorders and other diseases. Blood samples represent an easily accessible source of human cells for research and offer a host of practical advantages over the reliance on skin biopsies to attain cell samples. The breakthrough described here allows for study of...

2010-07-02 10:00:00

Residents with Polycythemia Vera in Bedford, Blair, Cambria and Somerset Counties Encouraged to Participate HARRISBURG, Pa., July 2 /PRNewswire-USNewswire/ -- The Pennsylvania Department of Health today announced a new, federally-funded study on the blood disorder Polycythemia vera, or PV, in Bedford, Blair, Cambria and Somerset counties. Residents of these counties who were diagnosed with PV between 2001 and 2008 are eligible to participate in the study and will be compensated. PV is...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'