Latest Red blood cell Stories

2009-12-07 19:31:53

Silencing a gene boosts production of a dormant, fetal form of hemoglobin A new genetic approach to treating sickle cell disease is showing promising results in mice, report researchers from Children's Hospital Boston. By inactivating a gene they previously discovered to be important in the laboratory, they were able to boost production of a healthy fetal form of hemoglobin in the mice, potentially compensating for the defective adult hemoglobin that causes red blood cells to "sickle" and...

2009-12-04 16:12:00

WINSTON-SALEM, N.C., Dec. 4 /PRNewswire-USNewswire/ -- A new, $2.8 million, four-year federal grant will support researchers at the University of Pittsburgh School of Medicine and their collaborators at Wake Forest University as they study why the quality of stored transfusion blood degrades over time and how to address the problem. This "storage lesion," as scientists call it, has been associated with increased risk for cardiovascular events and organ failure, particularly among...

2009-11-22 08:55:00

Fluid Dynamics Conference in Minneapolis next week highlights When people have malaria, they are infected with Plasmodium parasites, which enter the body from the saliva of a mosquito, infect cells in the liver, and then spread to red blood cells. Inside the blood cells, the parasites replicate and also begin to expose adhesive proteins on the cell surface that change the physical nature of the cells in the bloodstream. Experiments show that infected red blood cells are stiffer and stickier...

2009-11-16 07:00:00

Study highlights: - A liberal red blood cell (RBC) transfusion strategy to aggressively treat post-operative anemia in asymptomatic elderly patients undergoing hip fracture repair resulted in no statistically significant difference in cardiovascular outcomes (in-hospital ACS or mortality) as compared to a restrictive strategy of transfusing only for symptoms or hemoglobin less than 8 g/dL. - The primary endpoint of functional results (ability to walk unassisted) is still being analyzed to...

2009-10-26 14:35:42

What causes blood cells to deform, and how does deformation affect blood flow? Red blood cells, which make up 45 percent of blood, normally take the shape of circular cushions with a dimple on either side. But they can sometimes deform into an asymmetrical slipper shape. A team of physicists have used simulations to explore how fluid flow might be responsible for this deformation, as well as how the deformation in turn affects blood flow. The insights could help understand the mechanisms...

2009-10-23 09:49:15

A team of Harvard chemists led by X. Sunney Xie has developed a new microscopic technique for seeing, in color, molecules with undetectable fluorescence. The room-temperature technique allows researchers to identify previously unseen molecules in living organisms and offers broad applications in biomedical imaging and research. The scientists' results are published in the Oct. 22 issue of Nature. Partial funding for the project was provided by the National Science Foundation (NSF)....

2009-10-12 07:46:00

A gene with a significant effect on regulating hemoglobin in the body has been identified as part of a genome-wide association study, which looked at the link between genes and hemoglobin level in 16,000 people. The research was carried out by scientists from Imperial College London and published in Nature Genetics today. It shows a strong association between a gene known as TMPRSS6 and the regulation of hemoglobin. Hemoglobin is contained within red blood cells and is essential for...

2009-09-22 09:09:01

Severe trauma patients requiring a major transfusion are twice as likely to die if they receive red blood cells stored for a month or longer, according to research published in BioMed Central's open access journal Critical Care. The increased rate of death was measured up to six months post transfusion which is consistent with previous reports in cardiac surgery patients. Philip Spinella and Christopher Carroll, both pediatric intensivists from Connecticut Children's Medical Center, Hartford,...

2009-09-10 08:53:47

Children in Africa with sickle cell anaemia are dying unnecessarily from bacterial infections, suggests the largest study of its kind, funded by the Wellcome Trust. The results are published today in the journal the Lancet. The study has prompted calls for all children in Africa to receive vaccinations against the most common bacterial infections. Sickle cell anaemia affects millions of people worldwide, but more than eighty per cent of cases are in Africa, where 200,000 children are born...

2009-06-18 15:39:51

Researchers have identified a group of proteins that are targeted by parasites to cause malaria. "This study reveals the identity of a novel protein trafficking apparatus ... and hence, provides an 'Achilles heel' for anti-malaria drug developers," Brendan Crabb at the Burnet Institute in Melbourne, Australia and colleagues wrote in the journal Nature. Researchers from Australia and the United States noted the discovery of an encasing vacuole that is located inside infected cells. Parasites...

Word of the Day
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'