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Last updated on April 16, 2014 at 17:34 EDT

Latest Red blood cell Stories

2011-10-03 22:56:52

Researchers at St. Michael's Hospital have discovered a new function for an enzyme that may protect against organ injury and death from anemia. "Identifying this mechanism may lead to new therapies and approaches to improving outcomes for anemic patients," said Dr. Greg Hare, a researcher at the Li Ka Shing Knowledge Institute of the hospital and one of the lead investigators of the study. One in four people around the world and up to 50 per cent of patients coming for surgery are...

2011-09-29 09:22:43

Using a patient´s own stem cells, researchers at Johns Hopkins have corrected the genetic alteration that causes sickle cell disease (SCD), a painful, disabling inherited blood disorder that affects mostly African-Americans. The corrected stem cells were coaxed into immature red blood cells in a test tube that then turned on a normal version of the gene. The research team cautions that the work, done only in the laboratory, is years away from clinical use in patients, but should...

2011-09-22 11:08:42

More public awareness and education about sickle cell disease, an inherited disease that affects the blood system, is critically important, said a renowned hematologist from Baylor College of Medicine and Texas Children's Hospital. Dr. Russell E. Ware, professor of pediatrics at BCM, director of the Texas Children's Center for Global Health and director of the Texas Children's Hematology Center, offered information on the disease, what causes it, how it is treated and living with sickle...

2011-09-22 11:04:30

As researchers continue to study the use of hydroxyurea as a treatment for sickle cell disease, there is more evidence to validate that it is safe and effective for children with the disease, said an expert pediatric hematologist from Baylor College of Medicine. "We've known about this treatment since the 1960s," said Dr. Russell E. Ware, professor of pediatrics at BCM, director of the Texas Children's Center for Global Health and director of the Texas Children's Hematology Center. "It was...

2011-09-12 07:07:00

SAN DIEGO, Sept. 12, 2011 /PRNewswire/ -- HemaQuest Pharmaceuticals, Inc. (HemaQuest), a biotechnology company focused on developing small molecule therapeutics to treat hemoglobin disorders, announced today that it has completed enrollment in a randomized multi-dose Phase 2 study of HQK-1001 in patients with sickle cell disease. The study, initiated in April of this year, enrolled a total of 52 patients in clinical sites in the US, Canada, Jamaica, Egypt and Lebanon, and is designed to...

2011-09-01 15:35:16

For the first time, researchers have successfully injected cultured red blood cells (cRBCs) created from human hematopoietic stem cells (HSCs) into a human donor, according to study results published today in Blood, the Journal of the American Society of Hematology (ASH). As the global need for blood continues to increase while the number of blood donors is decreasing, these study results provide hope that one day patients in need of a blood transfusion might become their own donors. Using...

2011-08-31 10:58:00

ST. PAUL, Minn., Aug. 31, 2011 /PRNewswire-USNewswire/ -- Memorial Blood Centers is joining in celebrating September as Sickle Cell Awareness Month with a special appeal to potential sickle cell negative blood donors to step up and make a difference in the life of someone battling the pain of this chronic disease. Each year, about 1 in every 500 African-American infants are born with sickle cell--an inherited red blood cell disorder that also affects other populations, including people...

2011-08-04 14:07:16

Recent studies have shown that the heart contains cardiac stem cells that can contribute to regeneration and healing during disease and aging. However, little is known about the molecules and pathways that regulate these cells. Now, a new study utilizing a heart failure model is providing insight into one way to coax the cardiac stem cells into repairing the damaged heart. The research, published by Cell Press in the August 2011 issue of the journal Cell Stem Cell, finds that low doses of...

2011-07-20 14:45:21

A new study suggests young people with a serious genetic blood disorder are not getting the right help at school, especially pupils who miss lessons due to sickness. Research funded by the Economic and Social Research Council (ESRC) at De Montfort University, the University of York and Loughborough University reveals that most children with sickle cell disease (SCD) do not feel supported by schools in catching up on absences from class. Sickle cell is an inherited condition affecting around...

2011-07-18 14:34:27

A thalidomide analog is shaping up as a safe, worthy opponent of sickle cell disease, Georgia Health Sciences University researchers report. Much like hydroxyurea, the only Food and Drug Administration-approved therapy for sickle cell, pomalidomide increases production of fetal hemoglobin which, unlike its adult counterpart, cannot take on the destructive sickle shape. In stark contrast, pomalidomide also preserves bone marrow function actually increasing proliferation of the cells that make...