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Latest Reelin Stories

2011-02-09 15:04:29

The discovery of a new mechanism may have implications for a host of diseases A study from The Scripps Research Institute has unveiled a surprising mechanism that controls brain formation. The findings have implications for understanding a host of diseases, including some forms of mental retardation, epilepsy, schizophrenia, and autism. The research, led by Scripps Research Professor Ulrich Mueller, was published in the journal Neuron on February 10, 2011. In the new study, Mueller and...

2010-06-15 01:10:39

A molecule implicated in Alzheimer's disease interferes with brain cells by making them unable to "recycle" the surface receptors that respond to incoming signals, researchers at UT Southwestern Medical Center have found. The harmful molecule, called APOE4, is present in about one out of every six people, the researchers said. Those with the gene for APOE4 have up to 10 times the risk of developing Alzheimer's disease earlier in life than average. The researchers discovered that APOE4 makes a...

2009-10-06 14:27:11

The action of a small protein that is a major villain in Alzheimer's disease can be counterbalanced with another brain protein, researchers at UT Southwestern Medical Center have found in an animal study. The findings, available online in the journal Proceedings of the National Academy of Sciences, suggest a promising new tactic against the devastating illness, the researchers said. The harmful protein, called beta-amyloid, is found in the brain and, when functioning properly, suppresses...

2009-09-08 07:54:55

Researchers discover that the addition of the phosphor molecule to a the NMDA receptor in the brain is a necessary step in memory formation A new study that was carried out at the University of Haifa has identified another component in the chain of actions that take place in the neurons in the process of forming memories. This discovery joins a line of findings from previous studies that together provide a better understanding of the most complex processes in nature "“ the process of...

2009-03-03 08:57:57

Schizophrenia could be caused by faulty signaling in the brain, according to new research published today Schizophrenia could be caused by faulty signaling in the brain, according to new research published today in the journal Molecular Psychiatry. In the biggest study of its kind, scientists looking in detail at brain samples donated by people with the condition have identified 49 genes that work differently in the brains of schizophrenia patients compared to controls. Many of these genes...

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2007-03-14 11:50:14

Neurobiologists have discovered a mechanism by which the constantly changing brain retains memories"”from that dog bite to that first kiss. They have found that the brain co-opts the same machinery by which cells stably alter their genes to specialize during embryonic development. Courtney Miller and David Sweatt reported their findings in the March 15, 2007 issue of the journal Neuron, published by Cell Press. Their studies aimed at exploring whether a process called DNA methylation...

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2005-08-17 14:30:00

DALLAS -- Researchers at UT Southwestern Medical Center have identified a biochemical switch that affects how neurons fire in a part of the brain associated with learning, findings that may aid in understanding schizophrenia and Alzheimer's disease. The research sheds new light on the action of reelin, a protein known to be important in the nervous system. During development, reelin sends cues to migrating neurons, telling them where they're supposed to go. In adult mice, reelin has recently...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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