Latest Regeneration Stories

EAST NORRITON, Pa., Sept. 13 /PRNewswire/ -- Tengion, Inc. (Nasdaq: TNGN), a leader in regenerative medicine, announced today the publication of a key study in the American Journal of Physiology Renal Physiology by researchers at Tengion. In the study, rodents with chronic kidney disease (CKD) were treated with healthy kidney cells to catalyze the regeneration of functional kidney tissue and delay disease progression, as evidenced by extended survival, improved kidney filtration, and...

EAST NORRITON, Pa., Sept. 7 /PRNewswire/ -- Tengion, Inc. (Nasdaq: TNGN), a leader in regenerative medicine, today announced that Steven Nichtberger, M.D., President and Chief Executive Officer of Tengion, will present at the upcoming Rodman & Renshaw 12th Annual Healthcare Conference on Monday, September 13, 2010, at 2:50pm EDT. A live webcast of the presentation can be accessed under "Calendar of Events" in the Investors section of the Company's website at www.tengion.com. A replay...

Research implications include breast tissue regeneration and new cancer drug targetsFor the first time, researchers at Fred Hutchinson Cancer Research Center have identified and isolated adult mammary stem cells in mice. Long-term implications of this research may include the use of such cells to regenerate breast tissue, provide a better understanding of the role of adult stem cells in breast cancer development, and develop potential new targets for anti-cancer drugs.The findings, by Larry...

Great excitement greeted the discovery a few years ago that certain cells from mice and humans could be reprogrammed to become inducible pluripotent stem cells (iPS cells), as they hold promise for cell replacement therapy and modeling human disease. Two independent research groups "” one led by Ludovic Vallier, at the University of Cambridge, United Kingdom, and the other led by Holger Willenbring, at the University of California San Francisco "” have now shown that both possibilities...

A study led by a researcher at Albert Einstein College of Medicine of Yeshiva University has revealed a unique "partnership" between two types of bone marrow stem cells, which could lead to advances in regenerative medicine. The aim of regenerative medicine is to enable the body to repair, replace, restore or regenerate damaged or diseased cells, tissues and organs.The study was led by Paul Frenette, M.D., the new director of the Ruth L. and David S. Gottesman Institute for Stem Cell and...

'Landmark work' moves beyond the benchMayo Clinic investigators, with Belgian collaborators, have demonstrated that rationally "guided" human adult stem cells can effectively heal, repair and regenerate damaged heart tissue. The findings -- called "landmark work" in an accompanying editorial -- appear in today's Journal of the American College of Cardiology.Stem cells isolated from patients have normally a limited capacity to repair the heart. This innovative technology...

A protein known to be involved in a rare hereditary cancer syndrome may have a role in the regulation of liver stem cells and the development of liver cancer. In the August 15 issue of Genes & Development, a Massachusetts General Hospital (MGH) research team describes finding that the protein called merlin, encoded by the NF2 (neurofibromatosis type 2) gene, controls the activity of adult stem cells that give rise to the two major types of liver cells."We found that mutation of the...

Tissue regeneration a la salamanders and newts seems like it should be the stuff of science fiction. But it happens routinely. Why can't we mammals just re-grow a limb or churn out a few new heart muscle cells as needed? New research suggests there might be a very good reason: Restricting our cells' ability to pop in and out of the cell cycle at will "” a prerequisite for the cell division necessary to make new tissue "” reduces the chances that they'll run amok and form potentially...

Another option may be on the horizon for patients who lose limbs due to war, accident, or disease. Instead of using artificial legs or arms, patients actually may regrow their own missing limbs. An article in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine, focuses on research efforts to turn the long-standing dream of human limb regeneration into reality.C&EN Senior Editor Sophie Rovner notes that salamanders, flatworms, and certain other...

New research, published in the journal Development, by Dr. Anthony-Samuel LaMantia, professor of Pharmacology & Physiology and director of the newly formed GW Institute for Neuroscience, and his colleagues have identified the stem cells that generate three critical classes of nerve cells "“ olfactory receptors (ORNs), vomeronasal (VRNs) and gonadotropin releasing hormone (GnRH) neurons "“ that are responsible for enabling animals and humans, to eat, interact socially and...