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Latest Regeneration Stories

2011-05-12 22:20:21

Ever since animals, such as lizards and starfish, were observed regenerating missing body parts, people have wondered where the new tissues come from. In the case of the planarian flatworm, Whitehead Institute researchers have determined that the source of this animal's extraordinary regenerative powers is a single, pluripotent cell type. Most advanced animals, including mammals, have a system of specialized stem cells. In humans, we have blood stem cells in our bone marrow that make blood...

2011-05-12 22:18:51

A seldom-studied gene known as notum plays a key role in the planarian's regeneration decision-making process, according to Whitehead Institute scientists. Protein from this gene determines whether a head or tail will regrow at appropriate amputation sites. Since the late 1800s, scientists have been fascinated by the planarian's amazing ability to regenerate its entire body from a small wedge of tissue. Whitehead Member Peter Reddien and former postdoctoral fellow Christian Petersen recently...

2011-05-12 22:15:50

A single adult cell from one of the most impressive masters of regeneration in the animal kingdom "“ the planarian "“ is all it takes to build a completely functional new worm, researchers have learned. The study provides the first hard evidence that adult planarians harbor pluripotent stem cells "“ cells capable of producing the diverse range of tissue types necessary to build a complete animal. Distributed throughout the worm body, the newfound cells appear to have the...

2011-05-09 13:20:16

Researchers established a new method to patch a damaged heart with a tissue-engineering platform Researchers at Columbia Engineering have established a new method to patch a damaged heart using a tissue-engineering platform that enables heart tissue to repair itself. This breakthrough, recently published in the Proceedings of the National Academy of Sciences http://www.pnas.org/content/early/2011/04/19/1104619108.long, is an important step forward in combating cardiovascular disease, one of...

2011-05-09 12:37:39

Findings hold potential for solution to baldness, with wider implications for stem cell research In one of the first studies to look at the population behavior of a large pool of stem cells in thousands of hair follicles "“ as opposed to the stem cell of a single hair follicle "“ Keck School of Medicine of USC scientists deciphered how hair stem cells in mice and rabbits can communicate with each other and encourage mutually coordinated regeneration, according to an article...

2011-04-06 21:59:05

Move over, newts and salamanders. The mouse may join you as the only animal that can re-grow their own severed limbs. Researchers are reporting that a simple chemical cocktail can coax mouse muscle fibers to become the kinds of cells found in the first stages of a regenerating limb. Their study, the first demonstration that mammal muscle can be turned into the biological raw material for a new limb, appears in the journal ACS Chemical Biology. Darren R. Williams and Da-Woon Jung say their...

2011-04-05 08:00:00

FORT WORTH, Texas, April 5, 2011 /PRNewswire/ -- Healthpoint Biotherapeutics today announced that a new scientific review titled, Dynamic Reciprocity in the Wound Microenvironment, has been published in the March/April issue of Wound Repair and Regeneration. The manuscript authors-Drs. Gregory Schultz, Jeffrey Davidson, Robert Kirsner, Paul Bornstein and Ira Herman-are members of the Dynamic Reciprocity Work Group (DRWG), a scientific exploration committee convened by Healthpoint in 2008....

2011-04-01 16:21:28

Innovation in science This study establishes a unique system to perform in vivo RNAi screens for genetically dissecting the cellular signalling networks that regulate hepatocyte proliferation during chronic liver damage. Functional in vivo validation studies show that stable knockdown of the candidate gene by different shRNAs can significantly increase the repopulation efficiency of mouse hepatocytes and also increase the regenerative capacity of chronically damaged mouse livers. Such...

2011-03-29 07:38:00

CAMBRIDGE, Mass., March 29, 2011 /PRNewswire/ -- Pathfinder, LLC, a private biotechnology company focused on the treatment of diseases characterized by organ-specific cell damage ("Pathfinder"), today announced publication of promising preclinical data demonstrating that the Company's unique cell-based therapy is able to completely reverse diabetes in a mouse model. The results of the study, which will be printed in the April issue of Rejuvenation Research and available currently online,...

2011-03-23 10:54:00

EAST NORRITON, Pa., March 23, 2011 /PRNewswire/ -- Tengion, Inc. (Nasdaq: TNGN), a leader in regenerative medicine, today announced the addition of two renal research and clinical experts, Ben Humphreys, M.D., Ph.D. and Giuseppe Remuzzi, M.D., F.R.C.P., from the Harvard Stem Cell Institute and Mario Negri Institute respectively, to its panel of Research & Development Advisors. This panel provides counsel to Tengion and engages leading researchers, clinicians, and patient advocates with...


Word of the Day
ambsace
  • Bad luck; misfortune.
  • The smallest amount possible or the most worthless thing.
The word 'ambsace' comes from a Latin word meaning 'both'.