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Last updated on April 17, 2014 at 1:21 EDT

Latest Regulatory sequence Stories

2013-07-10 19:45:13

First-ever compendium of RNA sequences will be important guide to understanding the root of genetic diseases Every cell in an organism's body has the same copy of DNA, yet different cells do different things; for example, some function as brain cells, while others form muscle tissue. How can the same DNA make different things happen? A major step forward is being announced today that has implications for our understanding of many genetically-linked diseases, such as autism. Scientists...

2012-03-26 18:28:17

Knowing the molecular machinery Genome sequencing alone provides researchers with only limited information on the organism works because it neither reveals how the system is regulated nor does it indicate the role of each specific DNA sequence or RNA transcript. For that, scientists need to identify the system's regulatory and functional molecules, which are the ones calling the shots. A very well-established concept in molecular biology predicts that sequence conservation among species...

2009-11-19 19:17:15

A new statistical technique developed by researchers at the University of Illinois allows scientists to scan a genome for specific gene-regulatory regions without requiring prior knowledge of the relevant transcription factors. The technique has been experimentally validated in both the mouse genome and the fruit fly genome. "Our statistical approach is more widely applicable than other approaches, and is especially useful for investigating gene regulatory networks with relatively little...

2005-06-16 10:15:00

LIVERMORE, Calif. "” Scientists have tracked down the biological trigger that gives rise to Van Buchem disease, a hereditary, disfiguring bone disorder that can cause blindness and deafness. The findings provide insight into long-range gene regulation and could lead to new treatments for osteoporosis and other crippling bone disorders. A research team from Lawrence Livermore and Lawrence Berkeley national laboratories, the Novartis Institutes for BioMedical Research in Switzerland, and...