Latest Renal physiology Stories

Blood and urine tests could help doctors protect patients' kidneys Highlights     Many patients who undergo heart surgery experience kidney complications.     Blood and urine markers can indicate which surgery patients with injured kidneys will experience worsening kidney function.     Testing for these markers soon after heart surgery could help protect patients' kidneys. Blood and urine markers can indicate which patients with an abrupt kidney injury following heart...

Article is published in the American Journal of Physiology—Renal Physiology Nighttime visits to the bathroom are generally associated with being pregnant or having an enlarged prostate, but the problem can affect youngsters, too. A new study sheds light on why some children may need to urinate more often during the rest cycle. Danish researchers have found that sleep deprivation causes healthy children, between the ages of eight and twelve, to urinate significantly more frequently,...

New biomarkers tested How does a doctor determine whether or not an emergency-room patient has acute kidney injury? Using tests currently available in the hospital, this question is often difficult to answer. In many emergency cases, however, early diagnosis of the severity of the disease picture is crucial. A large multicenter study by clinicians of the Experimental and Clinical Research Center (ECRC), a joint cooperation between the Max Delbrück Center for Molecular Medicine (MDC)...

(Ivanhoe Newswire) – You kidneys may be a window into your health. In fact, measures of kidney health may predict premature death. A person's level of kidney function often indicates how likely they are to develop kidney failure and other conditions. Kidney function is most accurately represented by the kidneys' filtration rate, but this is difficult to measure. Therefore, blood levels of a protein called creatinine are commonly used to assess kidney function, but levels of two other...

Human blood test used as template for animal blood test When evaluating early kidney injuries in people, doctors monitor blood level increases of creatinine, a waste product of muscle breakdown, to understand the severity of the injury. Creatinine is filtered by the kidneys, and small increases are an indication of early damage to vital kidney function. For pets suffering critical illness or injury, University of Missouri researchers have found that even tiny increases of creatinine in...

Markers of kidney function also predict who is likely to die prematurely Highlights     Certain measures of kidney health can also predict who is likely to die prematurely.     Blood levels of the proteins creatinine, beta trace protein, and cystatin C may portray aspects of health that go beyond the kidneys.     Future studies should investigate whether a panel of markers of kidney function would provide a better prediction of an individual's prognosis than any one marker...

MOUNTAIN VIEW, Calif., Nov. 10, 2011 /PRNewswire/ -- ChemoCentryx, Inc. today announced positive preclinical results for its novel CCR2 antagonist at the 44th Annual Meeting of the American Society of Nephrology. CCR2 inhibition in diabetic mice resulted in rapid and robust improvements of albuminuria, serum markers of renal function, and hyperglycemia. These data were highlighted today in a poster presentation titled "CCR2 Inhibition in Diabetic Mice Results in a Rapid and Robust...

Clinicians can monitor kidney function with a simple equation Equations that estimate a patient's kidney function work as well as direct, invasive measurements, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). This means that many patients with chronic kidney disease (CKD) do not need to undergo the painful and cumbersome procedures that are performed to monitor kidneys' health. Measuring CKD patients' kidney function can help...

Markers may transform how kidney disease is diagnosedAcute kidney injury (AKI) is a common "“ but preventable -- complication after surgery that can lead to other complications or even death. The use and development of biomarkers will help physicians diagnose and treat acute kidney injury. Three protein measurements indicate who has a high risk of developing kidney injury after heart surgery, according to two studies appearing in an upcoming issue of the Journal of the American Society of...

A new animal study finds that too much or too little salt has an impact, and could lead to a lifetime of high blood pressure  A new animal study from Europe has drawn an association between pregnant mothers' sodium intake and their newborn's kidney development.  Among the most significant aspects of the study's findings is that either too much or too little salt during pregnancy had an adverse effect on the prenatal development of the offspring's kidneys. The consequence of such...