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Researchers Find Gene That Could Make It Easier To Develop

Researchers Find Gene That Could Make It Easier To Develop Life-saving Stem Cells

Michigan State University Not unlike looking for the proverbial needle in a haystack, a team of Michigan State University researchers have found a gene that could be key to the development of stem cells – cells that can potentially save...

Latest Reprogramming Stories

New Hope For Stem Cells For Application In Regenerative Medicine
2013-12-17 14:15:58

[ Watch The Video: Reprogramming Adult Somatic Cells to Pluripotency ] The Journal of Visualized Experiments Today, December 17, JoVE, the Journal of Visualized Experiments, has published a novel technique that could resolve a snag in stem cell research for application in regenerative medicine—a strategy for reprograming cells in vivo to act like stem cells that forgoes the risk of causing tumors. Dr. Kostas Kostarelos, principal investigator of the Nanomedicine Lab at the...

Mature Cells Revert Into Embryonic-like Stem Cells With Help From Physical Cues
2013-10-21 09:40:41

University of California - Berkeley Bioengineers at the University of California, Berkeley, have shown that physical cues can replace certain chemicals when nudging mature cells back to a pluripotent stage, capable of becoming any cell type in the body. The researchers grew fibroblasts cells taken from human skin and mouse ears on surfaces with parallel grooves measuring 10 micrometers wide and 3 micrometers high. After two weeks of culture in a special cocktail used to reprogram mature...

2012-03-30 00:20:01

Study Finds Out that a Protein called TRIM28 Preserves 'Epigenetic Marks' on a Specific Set of Genes.Singapore, Mar 30, 2012 - (ACN Newswire) - An international team led by scientists at A*STAR's Institute of Medical Biology (IMB) discovered that a protein called TRIM28, normally present in the mother's egg, is essential right after fertilisation[1] to preserve certain chemical modificationsor 'epigenetic marks' on a specific set of genes. This newly published study paves the way for more...

2012-03-29 22:13:18

1.            An international team led by scientists at A*STAR´s Institute of Medical Biology (IMB) discovered that a protein, called TRIM28, normally present in the mother´s egg, is essential right after fertilisation, to preserve certain chemical modifications or ℠epigenetic marks´ on a specific set of genes. This newly published study paves the way for more research to explore the role that epigenetics might play...

2011-12-02 01:50:56

FINDINGS: Tweaking the levels of factors used during the reprogramming of adult cells into induced pluriopotent stem (iPS) cells can greatly affect the quality of the resulting iPS cells, according to Whitehead Institute researchers. This finding explains at least in part the wide variation in quality and fidelity of iPS cells created through different reprogramming methods. RELEVANCE: Like embryonic stem cells, iPS cells can become any cell type in the body, a characteristic that could...

Important Step Identified In Sperm Reprogramming
2011-09-23 03:39:10

   When sperm meets egg, the chemical instructions that tag sperm cells must be erased so that human life can start anew. One way these instructions are erased is through demethylation, the removal of specific chemical tags or methyl groups that dot the underlying DNA of cells. Though scientists have known about this phenomenon for a decade, exactly how such "reprogramming" occurs has proved elusive. Now, a study from the University of North Carolina at Chapel Hill School of...

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2011-04-08 09:45:14

A paper published by Cell Press in the April 8th issue of the journal Cell Stem Cell reveals a new and more efficient method for reprogramming adult mouse and human cells into an embryonic stem cell-like state and could lead to better strategies for developing stem cells for therapeutic use. The ability to reprogram adult cells into cells that resemble embryonic stem cells has tremendous potential for both stem cell research and regenerative medicine. "Previous studies have demonstrated the...

2011-02-02 20:32:41

Reprogramming adult cells to recapture their youthful "can-do-it-all" attitude appears to leave an indelible mark, found researchers at the Salk Institute for Biological Studies. When the team, led by Joseph Ecker, PhD., a professor in the Genomic Analysis Laboratory, scoured the epigenomes of so-called induced pluripotent stem cells base by base, they found a consistent pattern of reprogramming errors. What's more, these incompletely or inadequately reprogrammed hotspots are maintained when...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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