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Latest Resistin Stories

Cholesterol Increased By Resistin Protein
2012-10-29 04:32:28

redOrbit Staff & Wire Reports - Your Universe Online In a discovery that could help prevent and treat heart disease, a team of Canadian researchers say that they have found a protein that can increase the production of low-density lipoprotein (LDL) cholesterol. The scientists, who presented their findings Sunday at the Canadian Cardiovascular Congress in Toronto, said that resistin, which is secreted by fatty tissue, causes human liver cells to produce more LDL, known as the "bad"...

Insulin Resistance Mediated By White Blood Cells
2012-08-06 09:00:59

Neutrophils' role is a surprise -- and a potential new target for treating diabetes Researchers at the University of California, San Diego School of Medicine say neutrophils, an abundant type of white blood cell typically tasked with attacking bacteria and other foreign invaders, also plays an unexpected role in mediating insulin resistance — the central characteristic of type 2 diabetes, which afflicts an estimated 26 million Americans. The findings are published in the August 5,...

2011-11-14 23:19:10

Male and female mice engineered to express the inflammatory enzyme IKKbeta in their fat tissue ate more but gained less weight. They burned sugar and fat more effectively than mice who were left unaltered. The research may shed light on how obesity and inflammation affect insulin resistance and sensitivity. In a new study, scientists report that they substantially curbed weight gain, improved metabolism, and improved the efficacy of insulin in mice by engineering them to express a specific...

2011-09-19 23:33:19

By using a mouse model of inflammation researchers at the University of Calgary have discovered a new class of molecules that can inhibit the recruitment of some white blood cells to sites of inflammation in the body. A provisional patent has been filed on these molecules by Innovates Calgary. When there is inflammation in the body, one of the primary defense mechanisms is the movement of white blood cells, known as neutrophils, from the bloodstream into the infected tissue. Neutrophils...

2011-09-05 11:40:18

Study finds inflammation may be part of the solution, not the problem Increased low-grade inflammation in the body resulting from obesity is widely viewed as contributing to type 2 diabetes. Going against this long-held belief, researchers from Children's Hospital Boston report that two proteins activated by inflammation are actually crucial for maintaining good blood sugar levels — and that boosting the activity of these proteins can normalize blood sugar in severely obese and...

2011-06-20 07:38:35

(Ivanhoe Newswire) -- Researchers have found a way to rid the body of stem cells that are responsible for driving fat expansion. The investigators discovered the first protein marker on the surface of adipose stromal cells (ASCs). These cells serve as progenitors of the cells that make up fat tissue. "Our long-term goal is to identify an approach to inactivate these cells in disease," Mikhail Kolonin of University of Texas Health Science Center at Houston, was quoted as saying. "By...

2011-06-16 21:28:41

Innovative adult stem cell research by scientists at The University of Texas Health Science Center at Houston (UTHealth) could aid efforts to apply the brakes to stem cells that produce the type of fat ringing the waists of millions. Research appeared today online ahead of the print issue of Cell Stem Cell. The scientists have developed a bold approach for targeting fat-generating stem cells that one day could aid in the delivery of drugs that slow the cells' ability to direct fat expansion....

2011-06-16 21:14:54

Researchers may have found the key to developing a method to rid the body of stem cells responsible for driving fat expansion. According to a report in the June 16 Cell Stem Cell, a Cell Press publication, they've landed the first protein marker on the surface of those so-called adipose stromal cells (ASCs), which serve as progenitors of the cells that make up fat tissue. "Our long-term goal is to identify an approach to inactivate these cells in disease," said Mikhail Kolonin of University...

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2010-09-07 13:46:07

Obesity and infertility frequently go hand in hand. Now, researchers reporting on studies of mice in the September issue of Cell Metabolism, a Cell Press publication, might have figured out why that is, and the results come as something of a surprise. "There was a sense that the reproductive dysfunction was due to insulin resistance," said Andrew Wolfe of Hopkins Children's. "What we propose is a fundamentally new model showing that different tissues respond to obesity differently and that...

2010-03-15 15:27:31

COLUMBUS, Ohio "“ An experimental oral drug has lowered blood sugar levels and inflammation in mice with Type 2 diabetes, suggesting that the medication could someday be added to the arsenal of drugs used by millions of Americans with this disease, according to new research. The drug consists of a synthetic molecule that stops the biological activity of a protein called macrophage migration inhibitory factor, or MIF. This protein is implicated in a number of diseases because it is...