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Latest Retinal Degeneration Stories

2010-02-17 08:34:10

Research by Johns Hopkins sensory biologists studying fruit flies, has revealed a critical step in fly vision. Humans with problems in this same step suffer retinal dystrophies, which manifest as visual defects ranging from mild visual impairments to complete blindness. The article, published Jan. 26 in Current Biology paves the way for using the fruit fly to screen for therapies to treat human retinal degeneration. Retinal dystrophies result from inherited defects in nearly every step of the...

2010-01-27 10:58:03

Researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts have developed a new tool for gene therapy that significantly increases gene delivery to cells in the retina compared to other carriers and DNA alone, according to a study published in the January issue of The Journal of Gene Medicine. The tool, a peptide called PEG-POD, provides a vehicle for therapeutic genes and may help researchers develop therapies for degenerative eye...

2010-01-19 11:34:29

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine have discovered new links between a common form of inherited blindness affecting children and a gene known as Abelson helper integration site-1 (AHI1). Their findings, which may lead to new therapies and improved diagnostics for retinal disease, will appear online in advance of publication in the journal Nature Genetics on January 17. A newly recognized class of disease known...

2009-10-24 13:00:00

PHILADELPHIA, Oct. 24 /PRNewswire/ -- Born with a retinal disease that made him legally blind, and would eventually leave him totally sightless, the nine-year-old boy used to sit in the back of the classroom, relying on the large print on an electronic screen and assisted by teacher aides. Now, after a single injection of genes that produce light-sensitive pigments in the back of his eye, he sits in front with classmates and participates in class without extra help. In the playground, he...

2009-10-22 12:13:10

Electronic eye implanted at NewYork-Presbyterian Hospital/Columbia mimics human retina A 50-year-old New York woman who was diagnosed with a progressive blinding disease at age 13 was implanted with an experimental electronic eye implant that has partially restored her vision. A team led by Dr. Lucian V. Del Priore at NewYork-Presbyterian Hospital/Columbia University Medical Center performed the June 26 surgery -- the first case of its kind in New York. The first treatment aimed at restoring...

2009-10-02 09:03:46

A new study reports that transplanted pigment-containing visual cells derived from human embryonic stem cells (hESCs) successfully preserved structure and function of the specialized light-sensitive lining of the eye (known as the retina) in an animal model of retinal degeneration. The findings, published by Cell Press in the October 2nd issue of the journal Cell Stem Cell, represent an exciting step towards the future use of cell replacement therapies to treat devastating degenerative eye...

2009-04-20 12:08:34

Omega three fatty acids protect brain cells by preventing the misfolding of a protein from a gene mutation in Parkinson's disease, U.S. researchers said. Dr. Nicolas Bazan of Louisiana State University and colleagues developed a cell model with a mutation of the Ataxin-1 gene. The defective Ataxin-1 gene induced the misfolding of the protein produced by the gene. The misshapened proteins cannot be properly processed by the cell machinery, resulting in tangled clumps of toxic protein that...

2009-04-03 11:14:23

Experiments with zebra fish are helping identify genes linked to retinal diseases that cause blindness, a Purdue University scientist said. Once we know the genetic network that influences retinal development, we can begin to understand the changes in specific genes that lead to vision loss, Yuk Fai Leung said. With such information, treatments could be developed to prevent or reverse diseases such as macular degeneration and diabetic retinopathy, he said. Using zebra fish, which are closer...

2009-03-31 08:50:25

St. Jude study findings suggest that therapies to restore vision in people with retinal degeneration should emphasize the use of other types of stem cells Cells isolated from the eye that many scientists believed were retinal stem cells are, in fact, normal adult cells, investigators at St. Jude Children's Research Hospital have found. If retinal stem cells could be obtained, they might provide the basis for treatments to restore sight to millions of people with blindness caused by retinal...

2009-03-30 16:03:00

St. Jude study findings suggest that therapies to restore vision in people with retinal degeneration should emphasize the use of other types of stem cells MEMPHIS, Tenn., March 30 /PRNewswire-USNewswire/ -- Cells isolated from the eye that many scientists believed were retinal stem cells are, in fact, normal adult cells, investigators at St. Jude Children's Research Hospital have found. If retinal stem cells could be obtained, they might provide the basis for treatments to restore sight to...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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