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Latest Retinitis pigmentosa Stories

2012-05-08 15:27:53

Gene therapy strategies to prevent and treat inherited diseases of the retina that can cause blindness have progressed rapidly. Positive results in animal models of human retinal disease continue to emerge, as reported in several articles published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The articles are available free on the Human Gene Therapy website. After 20 years of promising research, testing in animal models, and initial clinical trial...

Two Blind Men Receive Some Sight Through Eye Implants
2012-05-04 05:05:10

Two blind men have received sight for the first time in years due to new advances in medical science. The Oxford Eye Hospital and King's College Hospital in London have been carrying out a clinical trial that helps restore sight to the blind, at least partially, through eye implants. Chris James and Robin Millar lost their vision due to a condition known as retinitis pigmentosa, which is when the photoreceptor cells at the back of the eye eventually cease to function. A 0.12-inch...

2012-03-14 12:55:12

For the first time, scientists at the University of Wisconsin-Madison have made early retina structures containing proliferating neuroretinal progenitor cells using induced pluripotent stem (iPS) cells derived from human blood. And in another advance, the retina structures showed the capacity to form layers of cells — as the retina does in normal human development — and these cells possessed the machinery that could allow them to communicate information. (Light-sensitive...

2012-03-09 02:37:46

A newly developed, genetically modified pig may hold the keys to the development of improved treatments and possibly even a cure for retinitis pigmentosa (RP), the most common inherited retinal disease in the United States. The pig model was developed by researchers in the University of Louisville Department of Ophthalmology & Visual Sciences and at the National Swine Resource and Research Center at the University of Missouri. "We have previously relied mostly on rodent models to study...

2012-01-23 22:46:02

A new gene therapy method developed by University of Florida researchers has the potential to treat a common form of blindness that strikes both youngsters and adults. The technique works by replacing a malfunctioning gene in the eye with a normal working copy that supplies a protein necessary for light-sensitive cells in the eye to function. The findings are published today (Monday, Jan. 23) in the Proceedings of the National Academy of Sciences online. Several complex and costly steps...

2012-01-23 22:26:30

Members of a University of Pennsylvania research team have shown that they can prevent, or even reverse, a blinding retinal disease, X-linked Retinitis Pigmentosa, or XLRP, in dogs. The disease in humans and dogs is caused by defects in the RPGR gene and results in early, severe and progressive vision loss. It is one of the most common inherited forms of retinal degeneration in man. "Every single abnormal feature that defines the disease in the dogs was corrected following treatment,"...

2011-12-13 22:50:08

Research offers potential treatment for macular degeneration and retinitis pigmentosa Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A study by investigators at Mayo Clinic, Wayne State University and Johns Hopkins Medicine shows that steroids attached to the dendrimers target the damage-causing cells associated with neuroinflammation, leaving the rest of the eye unaffected and...

2011-12-13 15:10:32

Research at Wayne State University, Mayo Clinic and Johns Hopkins offers potential treatment for macular degeneration and retinitis pigmentosa Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A collaborative research study among investigators at Wayne State University, the Mayo Clinic and Johns Hopkins Medicine shows that steroids attached to the dendrimers targeted the damage-causing...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'