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Latest Retinoblastoma protein Stories

2013-05-09 23:04:11

A particular tumor suppressor gene that fights cancer cells does more than clamp down on unabated cell division -- the hallmark of the disease -- it also can help make cells more fit by allowing them to fend off stress, says a University of Colorado Boulder study. Boulder, CO (PRWEB) May 09, 2013 A particular tumor suppressor gene that fights cancer cells does more than clamp down on unabated cell division -- the hallmark of the disease -- it also can help make cells more fit by allowing...

2012-12-13 12:26:27

Researchers at Michigan State University have discovered a protein that does its best work with one foot in the grave. The study, which appears in the current issue of the Journal of Biological Chemistry, focuses on the nontraditional lifestyle of Retinoblastoma tumor suppressor proteins, which could lead to new ways to treat cancer. “Retinoblastoma proteins are unique in that they use controlled destruction to do their jobs in a timely but restrained fashion,” said Liang...

2011-12-13 22:57:01

Chemical disruption to key interaction shown to limit metastasis in test mice Finding ways to counteract or disrupt the invasive nature of cancer cells, called "metastasis," has been a long-term goal of cancer researchers. Now, researchers at Moffitt Cancer Center in Tampa, Fla., have identified an interactive pathway that regulates metastases in some cancers that may be vulnerable to chemical targeting in order to prevent cancer cell proliferation and tumor growth. Ongoing...

2010-04-13 14:58:50

The tumor suppressor Retinoblastoma represses DNA replication genes during senescence A frequently mutated gene in human cancers is the reitnoblastoma (RB) gene, which controls a potent tumor suppression pathway. Mutations in the gene disable the vast and intricate RB pathway in virtually all tumor cells, leading to disturbances in a host of cellular functions and ultimately provoking cancer. But which of these functions is crucial for the gene's tumor-suppressing activity has been...

2009-06-18 02:06:00

LAUSANNE, Switzerland and TAMPA, Florida, June 18 /PRNewswire/ -- Debiopharm Group (Debiopharm), a Swiss-based global biopharmaceutical group of companies with a focus on the development of prescription drugs that target unmet medical needs, and Moffitt Cancer Center (Moffitt), a non-profit Florida corporation, announce the signature of an exclusive license agreement for the development and commercialization of Debio 0928, a small molecule in early preclinical development that inhibits...

2008-10-13 15:00:11

U.S. medical scientists say they have identified a family of cancer-fighting molecules that help blood stem cells in mice decide when and how to divide. The Stanford University School of Medicine researchers say they discovered that blocking the molecules' function spurs the normally resting cells to begin proliferating strangely -- making too much of one kind of cell and not enough of another. The scientists note many types of human blood cancers involve a similar disruption in the...

2008-10-08 12:00:11

A family of cancer-fighting molecules helps blood stem cells in mice decide when and how to divide, say researchers at the Stanford University School of Medicine. Blocking the molecules' function spurs the normally resting cells to begin proliferating strangely -- making too much of one kind of cell and not enough of another. Many types of human blood cancers involve a similar disruption in the expression of that same family of molecules. The blood stem cells' misguided enthusiasm also...


Word of the Day
tesla
  • The unit of magnetic flux density in the International System of Units, equal to the magnitude of the magnetic field vector necessary to produce a force of one newton on a charge of one coulomb moving perpendicular to the direction of the magnetic field vector with a velocity of one meter per second. It is equivalent to one weber per square meter.
This word is named for Nikola Tesla, the inventor, engineer, and futurist.