Latest Retinoid X receptor Stories

2009-12-11 13:04:20

Following up on their previous work showing the rescue of dopamine neurons by chemicals that interact with the retinoid X receptor (RXR), researchers have now investigated the potential of these chemicals, known as RXR ligands, for the treatment of Parkinson's disease. Writing in the open access journal BMC Neuroscience the scientists describe the use of two cellular models of Parkinsonian damage to explore the neuroprotective function of the two RXR ligands LG268 and XCT. Susanna Kjellander...

2008-12-01 16:25:00

Compound shown to affect gene activity at extremely low concentrationsTributyltin, a ubiquitous pollutant that has a potent effect on gene activity, could be promoting obesity, according to an article in the December issue of BioScience. The chemical is used in antifouling paints for boats, as a wood and textile preservative, and as a pesticide on high-value food crops, among many other applications.Tributyltin affects sensitive receptors in the cells of animals, from water fleas to humans,...

2008-12-01 00:37:45

Two Japanese researchers say it is plausible and provocative to associate the obesity epidemic with chemical triggers present in the modern environment. Taisen Iguchi and Yoshinao Katsu of the Graduate University for Advanced Studies in Japan say the rise in obesity in humans over the past 40 years parallels the increased use of industrial chemicals during the same period. The researchers note the chemical Tributyltin is used as a wood and textile preservative in paints for boats, as a...

2005-08-11 21:10:00

DALLAS "“ Aug. 11, 2005 "“ Ongoing studies by researchers at UT Southwestern Medical Center and other institutions have uncovered the biochemical basis of many of the factors contributing to what is known as the metabolic syndrome, suggesting potential new drug targets for treating the condition. The metabolic syndrome, which affects more than 47 million Americans, is a constellation of disorders of the body's metabolism "“ such as abdominal obesity, hypertension and insulin...

Word of the Day
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.