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Latest Retinoids Stories

2007-12-30 03:00:07

By Hunter, Simon JOURNALS WATCH Too busy to catch up on the research? Let Dr Simon Hunter update you on recent papers Lung transplantation in cystic fibrosis N Engl J Med 2007; 357:2,143-52 Lung disease causes about 80 per cent of deaths in cystic fibrosis, with the median age at death being 25 years. The most aggressive therapy for this end-stage lung disease is lung transplantation. This study aimed to assess the effects of lung transplantation on survival and quality of life in...

2006-10-25 21:00:35

TEANECK, N.J., Oct. 25 /PRNewswire/ -- Eisai Inc., the U.S. pharmaceutical subsidiary of Tokyo-based Eisai Co., Ltd., today announces the completion of Eisai's acquisition of four oncology-related products from Ligand Pharmaceuticals. The companies were advised that the 30-day waiting period under the Hart-Scott-Rodino (HSR) act was terminated early by the Federal Trade Commission (FTC). In the agreement, Eisai Co., Ltd. and Eisai Inc. obtained exclusive global rights to ONTAK(R)...

2006-08-21 16:25:38

WASHINGTON (Reuters) - A well-known acne drug may increase cholesterol and other fat levels more than previously thought, U.S. researchers said on Monday. The drug isotretinoin, sold as Roche AG's Accutane as well as a generic, raised levels of triglyceride fats in about 44 percent of patients with previously normal levels, the University of California San Francisco analysis found. Total cholesterol levels were higher for 31 percent of patients. Previously, clinical trials of...

2006-08-21 16:25:00

WASHINGTON (Reuters) - A well-known acne drug may increase cholesterol and other fat levels more than previously thought, U.S. researchers said on Monday. The drug isotretinoin, sold as Roche AG's Accutane as well as a generic, raised levels of triglyceride fats in about 44 percent of patients with previously normal levels, the University of California San Francisco analysis found. Total cholesterol levels were higher for 31 percent of patients. Previously, clinical trials of Accutane showed...

2006-05-19 08:25:00

NEW YORK -- People with severe acne who achieve clearer skin with a combination of an oral antibiotic and anti-acne gels applied to the skin are often able to maintain their clearer complexion by using gels alone, according to two studies in the Archives of Dermatology. "This approach is especially attractive in an environment with rising concerns ... regarding long-term antibiotic use," note the authors of one report. For some people, acne may be so severe that a doctor may prescribe oral...

2006-04-26 14:36:54

NEW YORK (Reuters Health) - Low doses of isotretinoin (brand name, Roaccutane or Accutane) are effective for treating moderate acne, according to a study in the Journal of the American Academy of Dermatology. "The efficacy of isotretinoin at (regular doses) in the treatment of acne is well established and considered safe, although sometimes not easily tolerated because of its cutaneous side effects," Dr. Marcelo H. Grunwald, of Soroka University, Beer-Sheva, Israel, and colleagues...

2006-03-07 18:09:39

By Martha Kerr NEW YORK (Reuters Health) - Differin (adapalene gel 0.1%) used in combination with either topical or oral antibiotics is safe and effective for the treatment of moderate to moderately severe acne. Results of a phase IV multicenter trial were presented in San Francisco at the annual meeting of the American Academy of Dermatology. The 12-week study of the topical retinoid gel involved 1,979 patients and more than 400 practicing dermatologists. The dermatologists were...

2006-02-23 15:15:00

By Susan Heavey WASHINGTON (Reuters) - The Food and Drug Administration on Thursday said it will implement new restrictions on a widely used acne drug next Wednesday in an effort to curb birth defects, rejecting calls from some doctors to delay the program. Some doctors have said the revised limits on prescribing Accutane, sold by Switzerland's Roche AG but also available in generic form, are too cumbersome and take up too much time. Dermatologists had asked the agency to delay the program...

2006-02-10 15:56:16

By Lisa Richwine GAITHERSBURG, Maryland (Reuters) - A plan to prevent birth defects from a widely used acne drug is placing heavy burdens on doctors, patients and pharmacists and should be halted until flaws can be fixed, doctors said on Friday. The restrictions on Roche AG's Accutane or generic versions are so cumbersome and time-consuming they may send patients to the Internet, where medicines may be counterfeit and there are no safeguards to prevent pregnancy, critics said....

2006-02-10 15:55:00

By Lisa Richwine GAITHERSBURG, Maryland (Reuters) - A plan to prevent birth defects from a widely used acne drug is placing heavy burdens on doctors, patients and pharmacists and should be halted until flaws can be fixed, doctors said on Friday. The restrictions on Roche AG's Accutane or generic versions are so cumbersome and time-consuming they may send patients to the Internet, where medicines may be counterfeit and there are no safeguards to prevent pregnancy, critics said. Accutane is the...