Quantcast

Latest Retrovirus Stories

2009-11-12 11:43:25

The AIDS virus inserts its genetic material into the genome of the infected cell. Scientists of the German Cancer Research Center have now shown for the first time that the virus almost entirely spares particular sites in the human genetic material in this process. This finding may be useful for developing new, specific AIDS drugs. Like all retroviruses, the AIDS virus (HIV) integrates its DNA into the genome of the infected cell. As integration sites, HIV usually prefers active genes that...

2009-10-15 14:02:21

By discovering the atomic structure of a key human enzyme, researchers at The University of Texas at Austin have pointed the way toward designing anti-HIV drugs with far less toxic side effects. Their work was published this week in Cell. "Many anti-HIV drugs are designed to stop the process of DNA replication," says Dr. Whitney Yin, assistant professor of chemistry and biochemistry. "That turns out to be a great thing to do to help cure virus infections, because it stops the processes of...

97a3e22ac131aa10957d248c7361b2071
2009-07-16 14:55:00

Surprising findings may yield insights into human developmental disorders A single evolutionary event appears to explain the short, curved legs that characterize all of today's dachshunds, corgis, basset hounds and at least 16 other breeds of dogs, a team led by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, reported today. In addition to what it reveals about short-legged dogs, the unexpected discovery provides new clues about how physical...

2009-06-26 08:05:00

Discovery may offer potential strategy for therapies to clear HIVScientists at the Gladstone Institutes of Virology and Immunology (GIVI) have found another clue that may lead to eradication of HIV from infected patients who have been on antiretroviral therapy. A real cure for HIV has been elusive because the virus can "hide" in a latent form in resting CD4-T cells. By understanding this "latency" effect, researchers can identify ways to reactivate the virus and enable complete clearance by...

2009-06-25 11:27:32

Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells. In particular, miR29 plays a key role in controlling the HIV life cycle. The study suggests that HIV may have co-opted this cellular defense mechanism to help the virus hide from the immune system and antiviral drugs. The research was published today in the journal Molecular...

2009-06-11 15:40:00

Gene insertions have implications for understanding development of genetic diseases, cancerJumping genes do most of their jumping, not during the development of sperm and egg cells, but during the development of the embryo itself. The research, published this month in Genes and Development, "challenges standard assumptions on the timing of when mobile DNA, so-called jumping genes, insert into the human genome," says senior author Haig H. Kazazian Jr., MD, Seymour Gray Professor of Molecular...

bb87df651c7001cdd59dcca39ecbcf6f1
2009-05-20 07:46:31

Those traveling abroad should take seriously advice to pack their condoms and keep their needles to themselves: research published today in the open access journal Retrovirology shows that tourists, travelers and migrants from Greece, Portugal, Serbia and Spain actively export HIV-1 subtype B to other European nations. An international team of scientists used samples from 17 European countries to construct a viral phylogeography "“ a geographic pattern of genetic information taken from...

2009-05-18 09:44:28

A team of University of Oregon biologists, using fruit flies, has created a way to isolate RNA from specific cells, opening a new window on how gene expression drives normal development and disease-causing breakdowns.While DNA (deoxyribonucleic acid) provides an identical genetic blueprint in every cell, RNA (ribonucleic acid) decodes genetic instructions that turn protein molecules on and off in different cell types.The new tagging method, tested in a variety of subsets of Drosophila brain...

2009-03-06 10:09:42

 In a collaborative study with the World Health Organization and seven other laboratories, researchers at the Stanford University School of Medicine have compiled a list of 93 common mutations of the AIDS virus associated with drug resistance that will be used to track future resistance trends throughout the world.The researchers analyzed data from about 15,220 patients across the globe to develop an updated and accurate list of the most common, resistance-related mutations of the virus....

044eba1cc2a792d559c8f67802cff3511
2009-01-19 11:30:35

Researchers at the Max Planck Institute for Developmental Biology in Tbingen, Germany, determined the structure of a protein (L1ORF1p), which is encoded by a parasitic genetic element and which is responsible for its mobility. The so-called LINE-1 retrotransposon is a mobile genetic element that can multiply and insert itself into chromosomal DNA at many different locations. This disturbs the genetic code at the site of integration, which can have serious consequences for the organism. On the...


Word of the Day
conjunto
  • A style of popular dance music originating along the border between Texas and Mexico, characterized by the use of accordion, drums, and 12-string bass guitar and traditionally based on polka, waltz, and bolero rhythms.
The word 'conjunto' comes through Spanish, from Latin coniūnctus, past participle of coniungere, to join together; see conjoin