Latest Rhabdoviridae Stories
An intriguing new virus from the Democratic Republic of Congo (DRC) has been identified as the cause of a deadly outbreak of acute hemorrhagic fever, which killed two people and left one gravely ill in the summer of 2009.
Vesicular stomatitis virus, or VSV, has long been a model system for studying and understanding the life cycle of negative-strand RNA viruses, which include viruses that cause influenza, measles and rabies.
Vesicular stomatitis virus (VSV) is a virus in the family Rhabdoviridae. Rabies is in the same family. VSV infects insects and animals and is important to farmers in certain regions of the world where it can infect cattle. It is a common laboratory virus used for studying the Rhabdoviridae family and viral evolution. It is the prototypic member of the vesiculovirus genera of the Rhabdovirus family. The genome is a single molecule of negative-sense RNA that encodes five major proteins.
The rabies virus is neurotropic virus, transmissible through the saliva of animals, that causes fatal disease in human and animals. Rabies is the type species of the Lyssavirus genus of Rhabdovirdae family. They are enveloped and single stranded RNA genome with negative-sense. All replication takes place in the cytoplasm. The virus has a bullet-like shape. Rabies enters the host cells through the endosomal transport pathway after receptor binding. After entry transcription of the viral...
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