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Latest rheumatism Stories

2011-03-08 15:44:12

Modified-release therapy is well tolerated in clinical trial Researchers in Europe reported that treatment with modified-release sildenafil significantly reduced the frequency of attacks of Raynaud's phenomenon in patients with limited cutaneous systemic sclerosis (lcSSc), also known as scleroderma. The double-blind, placebo-controlled trial found that sildenafil was well tolerated with only some subjects experiencing minor or moderate side effects. Full findings are available in the March...

2011-03-08 15:35:49

Combination therapy for rheumatoid arthritis has consistent safety profile A recent trial of rituximab in combination with a tumor necrosis factor (TNF) inhibitor and methotrexate (MTX) in patients with active rheumatoid arthritis (RA) found the safety profile to be consistent with other RA trials with TNF inhibitors. While the trial reported no new safety risks, clear evidence of an efficacy advantage in RA patients receiving the combination therapy was not observed in this study sample....

2011-03-02 07:00:00

ATLANTA and PORTLAND, Ore., March 2, 2011 /PRNewswire-USNewswire/ -- Two leading patient advocacy organizations have joined forces to educate people about psoriatic arthritis, an inflammatory disease that can lead to joint damage, especially if not diagnosed and treated early. The Joint Smart Coalition, launched today by the Arthritis Foundation and the National Psoriasis Foundation in collaboration with Amgen and Pfizer, aims to provide empowering and educational resources for people with...

2011-03-02 07:30:00

THOUSAND OAKS, Calif. and COLLEGEVILLE, Pa., March 2, 2011 /PRNewswire/ -- World-class professional golfer and psoriatic arthritis patient Phil Mickelson today launches "On Course with Phil," a disease education program for people with certain chronic inflammatory joint and skin conditions, in partnership with Amgen (Nasdaq: AMGN) and Pfizer, Inc. (NYSE: PFE). This program seeks to inspire patients with psoriatic arthritis, rheumatoid arthritis or plaque psoriasis to take action, educate...

2011-02-03 18:50:13

The American College of Rheumatology today announced the release of two new provisional definitions of rheumatoid arthritis remission, which are to be applied to future RA clinical trials. According to research presented in the March issue of Arthritis & Rheumatism, a person with RA who is enrolled in a clinical trial would need to meet one of the following definitions to be considered in remission: 1. Tender joint count, swollen joint count (on 28 joint counts), C-reactive protein (in...

2011-01-27 14:24:50

Activation of interferon signaling pathway may cause premature plaque build-up Researchers in China have demonstrated interferon-alpha (IFN-a) is associated with increased risk of atherosclerosis in patients with systemic lupus erythematosus (SLE). For the first time, IFN-a priming was shown to promote lipid uptake and foam cell formation"”a crucial step in plaque build-up. This activation of the IFN signaling pathway may be linked to the premature atherosclerosis risk in SLE. Full...

2011-01-27 14:16:13

In rheumatoid arthritis patients unresponsive to biologic agents In a previous study, rheumatoid arthritis (RA) patients who failed to respond to methotrexate were shown to experience positive results with fostamatinib disodium (R788), an oral spleen tyrosine kinase (Syk) inhibitor that is thought to block immune cell signaling involved with bone and cartilage destruction. In the current study, RA patients who failed to respond to biologic agents were studied. In contrast to the prior study,...

2011-01-18 21:59:46

Study shows high physical activity helps people with osteoarthritis walk faster When a traffic light at a busy intersection flashes the WALK sign, people with knee osteoarthritis worry they can't walk fast enough to make it across the street in time. New Northwestern Medicine research shows people with this common arthritis are more likely to walk fast enough if they lead physically active lives.  "The more active people are, the faster they can walk," said Dorothy Dunlop, associate...

2011-01-04 14:12:00

Past smoking history does not affect RA patients' response to treatments Patients with early rheumatoid arthritis (RA) who are current smokers were less likely to achieve good response to methotrexate (MTX) and tumor necrosis factor (TNF) inhibitors than those who never smoked. The study by researchers from Sweden also found that RA patients who smoked in the past did not experience a lower response to these therapies. Results of the 10-year study appear in the January 2011 issue of Arthritis...

2011-01-04 14:10:00

New research finds pattern for detecting 'false-positive' ANA results The presence of antinuclear antibodies (ANA) indicates the possibility of autoimmunity and the indirect immunofluorescence (IIF) assay on HEp-2 cells is the standard blood test (ANA-HEp-2) used to detect ANA. However, studies have shown that a "false-positive" ANA test occurs in up to 13% of healthy individuals. In such cases the test detects the presence of autoantibodies that apparently are not associated with...


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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