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Latest Ribosome Stories

2014-06-06 09:56:06

PLOS YbeY is a conserved protein that is present in most bacteria. A study published on June 5th in PLOS Pathogens examines the function of YbeY in the cholera bacterium and reveals critical roles in RNA metabolism in this and other pathogenic bacteria. Graham Walker, from the Massachusetts Institute of Technology, USA, and colleagues previously studied E. coli YbeY and found that it acts as an "RNase"—a protein that deliberately and specifically cuts RNA molecules and thereby...

2014-04-18 14:05:01

Scientists studying the most common form of inherited mental disability—a genetic disease called “Fragile X syndrome”—have uncovered new details about the cellular processes responsible for the condition that could lead to the development of therapies to restore some of the capabilities lost in affected individuals. In a paper that will be published in the May 8 Molecular Cell, but is being made available this week in the early online edition of the journal, the researchers show...

2014-04-04 11:48:17

Not so long ago researchers thought that RNAs came in two types: coding RNAs that make proteins and non-coding RNAs that have structural roles. Then came the discovery of small RNAs that opened up whole new areas of research. Now researchers have come full circle and predicted that some long non-coding RNAs can give rise to small proteins that have biological functions. A recent study in The EMBO Journal describes how researchers have used ribosome profiling to identify several hundred long...

2014-04-01 13:16:37

Ribosomes are essential for life, generating all of the proteins required for cells to grow. Mutations in some of the proteins that make ribosomes cause disorders characterized by bone marrow failure and anemia early in life, followed by elevated cancer risk in middle age. These disorders are generally called "ribosomopathies." How can ribosomopathies first appear as diseases caused by too few cells, but later turn into diseases caused by too many cells? This paradox has puzzled the...

2014-03-31 23:23:41

Why do mutations in the proteins that make ribosomes cause bone marrow failure and anemia early in life, followed by elevated cancer risk in middle age? A new University of Maryland-led study suggests these disorders, called ribosomopathies, are caused by a sequence of mistakes at the molecular level. College Park, MD (PRWEB) March 31, 2014 Ribosomes are essential for life, generating all of the proteins required for cells to grow. Mutations in some of the proteins that make ribosomes...

2014-02-13 10:36:55

Ribosomes, the cellular machines that build proteins, are themselves made up of dozens of proteins and a few looping strands of RNA. A new study, reported in the journal Nature, offers new clues about how the ribosome, the master assembler of proteins, also assembles itself. "The ribosome has more than 50 different parts – it has the complexity of a sewing machine in terms of the number of parts," said University of Illinois physics professor Taekjip Ha, who led the research with U. of...

Mitochondrial Ribosome Deciphered
2014-01-24 13:37:28

ETH Zurich Researchers at the Swiss Federal Institute of Technology (ETH) in Zurich have deciphered the structure of part of the ribosome found in mitochondria, the power plants of the cell. The scientists were able to benefit from advancements in the field of electron microscopy and capture images of the mitochondrial ribosome at a level of resolution never achieved before. The ribosome can be thought of as a decryption device housed within the cell. It is able to decipher the genetic...

Naked Mole Rat Longevity Perfect Proteins
2013-10-01 08:41:31

redOrbit Staff & Wire Reports - Your Universe Online Researchers from the University of Rochester believe they have discovered the secret behind the longevity of the world’s longest-lived rodent: the creatures produce better protein than other members of their order. Naked mole rats, which typically live approximately 30 years and tend to remain healthy until their final days, possess a unique mechanism for building proteins, according to a recently-published study from research...

2013-07-01 11:55:56

Synthetic biology technology could lead to new antibiotics, modified protein-generators Synthetic biology researchers at Northwestern University, working with partners at Harvard Medical School, have for the first time synthesized ribosomes -- cell structures responsible for generating all proteins and enzymes in our bodies -- from scratch in a test tube. Others have previously tried to synthesize ribosomes from their constituent parts, but the efforts have yielded poorly functional...

This Image May Lead To Better Antibiotics
2013-06-28 13:45:14

Lawrence Berkeley National Laboratory Berkeley Lab scientists create atomic-scale structure of ribosome attached to a molecule that controls its motion This may look like a tangle of squiggly lines, but you're actually looking at a molecular machine called a ribosome. Its job is to translate DNA sequences into proteins, the workhorse compounds that sustain you and all living things. The image is also a milestone. It's the first time the atom-by-atom structure of the ribosome has been...


Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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