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Latest Ribosome Stories

2010-12-13 14:27:07

Like an overprotective parent on the first day of school, a targeting factor sometimes needs a little push to let go of its cargo. Scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have visualised one such hand-over. They were the first to determine the structure of a ribosome-protein complex involved in carrying nascent proteins out of the cell. Their work, published online today in Nature Structural and Molecular Biology, could increase understanding of...

2010-12-06 14:05:24

Einstein College of Medicine research shows certain genes are 'clueless' Scientists at Albert Einstein College of Medicine of Yeshiva University have made an unexpected finding about the method by which certain genes are activated. Contrary to what researchers have traditionally assumed, genes that work with other genes to build protein structures do not act in a coordinated way but instead are turned on randomly. The surprising discovery, described in the December 5 online edition of Nature...

2010-10-29 19:16:52

Work could help unravel complexities of the cell and lead to new antibiotics and disease treatments A team from The Scripps Research Institute has revealed the first-ever pictures of the formation of cells' "protein factories." In addition to being a major technical feat on its own, the work could open new pathways for development of antibiotics and treatments for diseases tied to errors in ribosome formation. In addition, the techniques developed in the study can now be applied to other...

2010-09-13 12:02:53

The findings could lead to new understanding of neurodegenerative diseases Scientists from The Scripps Research Institute have solved a long-standing mystery of how cells conduct "quality control" to eliminate the toxic effects of a certain kind of error in protein production. The findings may lead to a better understanding of a host of neurodegenerative diseases. The research was published in an advance, online issue of the journal Nature on September 12, 2010. "It is exciting because we are...

2010-08-16 18:28:05

FINDINGS: Short pieces of RNA, called microRNAs, control protein production primarily by causing the proteins' RNA templates (known as messenger RNA or mRNA) to be disabled by the cell, according to Whitehead Institute scientists. RELEVANCE: Researchers have known that mammalian microRNAs control protein production by causing the mRNAs to degrade, but they have wondered how much additional effects microRNAs impart by jamming the process that translates mRNAs into proteins. These results from...

2010-04-17 12:28:09

In a multidisciplinary approach, Professor Yves Barral, from the Biology Department at ETH Zurich and the computer scientists Dr. Gina Cannarozzi and Professor Gaston Gonnet, from the Computer Science Department of ETH Zurich and the SIB Swiss Institute of Bioinformatics, joined forces to chase possible sub-codes in genomic information. The study, which will be published in today's issue of the journal Cell, led to the identification of novel sequence biases and their role in the control of...

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2010-04-12 14:08:40

With few exceptions, all known forms of life on our planet rely on the same genetic code to specify the amino acid composition of proteins. Although different hypotheses abound, just how individual amino acids were assigned to specific three-letter combinations or codons during the evolution of the genetic code is still subject to speculation. Taking their hints from relics of this evolution left behind in modern cells, researchers at the Salk Institute for Biological Studies concluded that...

2010-02-01 18:05:45

Johns Hopkins scientists believe they may have figured out how genetic snippets called microRNAs are able to shut down the production of some proteins. The issue, they say, is important because the more scientists know about how genes "” the blueprints for proteins "” are regulated, the more likely they are to figure out how to use that information in treating or preventing diseases linked to such regulation, including cancer. In both computer and test-tube studies using fruit-fly...

2010-01-27 08:21:50

Researchers at the University of Illinois at Chicago and Israel's Weizmann Institute of Science have found that two antibiotics working together might be more effective in fighting pathogenic bacteria than either drug on its own. Individually, lankacidin and lankamycin, two antibiotics produced naturally by the microbe streptomyces, are marginally effective in warding off pathogens, says Alexander Mankin, professor and associate director of the UIC Center for Pharmaceutical Biotechnology and...

2010-01-14 13:10:09

When ribosomes produce protein in all living cells, they do so through a chemical reaction that happens so fast that scientists have been puzzled. Using large quantum mechanical calculations of the reaction center of the ribosome, researchers at Uppsala University in Sweden can now provide the first detailed picture of the reaction. The findings are published in the Web edition of Proceedings of the National Academy of Sciences, PNAS. It was previously known how the chemical reaction goes...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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