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Latest Ribozymes Stories

2011-05-20 12:53:28

Berkeley Lab scientists reveal how protein-making machine bends without breaking It sounds like hype from a late-night infomercial: It can twist and bend without breaking! And wait, there's more: It could someday help you fend off disease! But in this case it's true, thanks to scientists from several institutions including the U.S. Department of Energy's Lawrence Berkeley National Laboratory. They derived atomic-scale resolution structures of the cell's protein-making machine, the ribosome,...

2011-02-23 13:16:32

Researchers at the University of Illinois at Chicago have discovered a signaling mechanism in the bacterial ribosome that detects proteins that activate genes for antibiotic resistance. "The ribosome is one of the most complex molecular machines in the cell," said Alexander Mankin, UIC professor and director of the Center for Pharmaceutical Biotechnology. It is responsible for the production of all proteins in the cell, and in bacteria it is one of the major antibiotic targets. Understanding...

2010-12-23 02:18:44

Findings could point to possible new target for cancer studies, potential treatments A scientist from the Florida campus of The Scripps Research Institute has discovered a molecular switch that controls the synthesis of ribosomes. Ribosomes are the large machineries inside all living cells that produce proteins, the basic working units of any cell. These new findings offer a novel target for potential treatments for a range of diseases, including cancer. The study is published in the December...

2010-10-29 19:16:52

Work could help unravel complexities of the cell and lead to new antibiotics and disease treatments A team from The Scripps Research Institute has revealed the first-ever pictures of the formation of cells' "protein factories." In addition to being a major technical feat on its own, the work could open new pathways for development of antibiotics and treatments for diseases tied to errors in ribosome formation. In addition, the techniques developed in the study can now be applied to other...

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2010-10-05 08:36:57

Supercomputer simulations at the Department of Energy's Oak Ridge National Laboratory are helping scientists unravel how nucleic acids could have contributed to the origins of life. A research team led by Jeremy Smith, who directs ORNL's Center for Molecular Biophysics and holds a Governor's Chair at University of Tennessee, used molecular dynamics simulation to probe an organic chemical reaction that may have been important in the evolution of ribonucleic acids, or RNA, into early life...

2010-01-14 13:10:09

When ribosomes produce protein in all living cells, they do so through a chemical reaction that happens so fast that scientists have been puzzled. Using large quantum mechanical calculations of the reaction center of the ribosome, researchers at Uppsala University in Sweden can now provide the first detailed picture of the reaction. The findings are published in the Web edition of Proceedings of the National Academy of Sciences, PNAS. It was previously known how the chemical reaction goes...

2009-11-15 12:18:59

Combination drug therapy has become a staple for treating many infections. For instance, doctors treat extensively drug resistant forms of tuberculosis with one drug that breaks down the pathogen's protective barriers and opens the door for another to deliver the deathblow. Just as some drugs work better together, however, other pairings are counter-productive. "The question we asked was how can it be that two drugs in combination are less effective than one of them alone," said senior author...

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2009-10-07 13:35:00

Three scientists were awarded the Nobel chemistry prize Wednesday for their groundbreaking work in mapping the ribosome, which creates protein for human life. The Royal Swedish Academy of Sciences announced that Venkatraman Ramakrishnan, Thomas A. Steitz and Ada E. Yonath would receive the chemistry award for using X-ray crystallography to show what a ribosome looks like and how it functions at the atomic level. Ribosomes are responsible for the creation of proteins: oxygen-transporting...

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2009-04-30 08:37:02

Scientists at Scripps Research make molecules that evolve and compete, mimicking behavior of Darwin's finches As described in an article published this week in an advance, online edition of the journal Proceedings of the National Academy of Sciences (PNAS), the work demonstrates some of the classic principles of evolution. For instance, research shows that when different species directly compete for the same finite resource, only the fittest will survive. The work also demonstrates how, when...

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2009-02-04 10:51:28

A mathematical model developed at the Weizmann Institute has revealed how single-celled organisms regulate their activities for maximum efficiency The bacterium Escherichia coli, one of the best-studied single-celled organisms around, is a master of industrial efficiency. This bacterium can be thought of as a factory with just one product: itself. It exists to make copies of itself, and its business plan is to make them at the lowest possible cost, with the greatest possible efficiency. ...


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
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