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Latest Richard J. Solove Research Institute Stories

2012-12-12 23:28:43

-People who develop chronic lymphocytic leukemia (CLL) are typically age 65 and older, but participants in CLL clinical trials are usually several years younger; -The age of CLL patients is not usually considered when determining treatment; -This study suggests that older and younger CLL patients require different therapy. Doctors should use different therapies when treating older and younger patients with chronic lymphocytic leukemia, according to a new study led by researchers at the...

2012-03-12 14:15:59

Researchers have identified a molecule that helps control the severity of graft-versus-host disease, a life-threatening complication for many leukemia patients who receive a bone-marrow transplant. The study, led by researchers with the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), used an animal model and tissues from human patients to show that high levels, or over-expression, of...

2012-01-03 14:52:35

A new study shows that it is possible to selectively target and block a particular microRNA that is important in liver cancer. The finding might offer a new therapy for this malignancy, which kills an estimated 549,000 people worldwide annually.   The animal study, by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) and at Mayo Clinic, focused on microRNA-221...

2011-12-21 14:59:10

The study shows how normal cells in tumors can enhance the growth of the tumor´s cancer cells after losing an important tumor suppressor gene called Pten.   The findings suggest a new strategy for treating breast cancer by interrupting signals between normal cells and cancer cells in tumors.    A new study published in the journal Nature Cell Biology has discovered how normal cells in tumors can fuel tumor growth.   Led by researchers at the Ohio State...

2011-12-15 16:50:59

A new study has identified a gene mutation that researchers estimate dates back to 11,600 B.C., making it the second oldest human disease mutation yet discovered.   Researchers with the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute led the study and estimate that the mutation arose in the Middle East some 13,600 years ago. Only a mutation seen in cystic fibrosis that arose between 11,000 and 52,000...

2011-12-02 13:47:02

Men are three times more likely than women to develop a common form of skin cancer but medical science doesn´t know why. A new study may provide part of the answer.   Researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) have found that male mice had lower levels of an important skin antioxidant than female mice and higher levels of certain cancer-linked...

2011-05-16 17:30:30

Adding low doses of the targeted agent sorafenib to the chemotherapy and radiation now often used to treat head and neck cancer might significantly improve patient care and quality of life, according to a new study by researchers at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC "“ James). The findings suggest that adding sorafenib would maintain treatment efficacy while permitting the use of lower...

2011-05-05 15:02:32

In a rare and medically remarkable operation, a multi-disciplinary team of surgeons at the Ohio State University Comprehensive Cancer Center "“ Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC "“ James) removed the left leg, hip and pelvis of a cancer patient, and used the healthy, living bones from his amputated leg to completely rebuild the connection between his spine and remaining right pelvis to support a high-tech prosthetic leg. "This...

2011-02-22 21:16:54

A cancer-causing retrovirus exploits key proteins in its host cells to extend the life of those cells, thereby prolonging its own survival and ability to spread, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center "“ Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC "“ James) and Ohio State's College of Veterinary Medicine. The human T-lymphotropic virus type-1 (HTLV-1), which causes adult T-cell leukemia...

2011-01-25 14:53:20

A study shows for the first time that the three most common chromosome changes seen in chronic lymphocytic leukemia disrupt a molecular network that includes several important genes and strongly influences the outcome of the disease. The research was led by investigators at the Ohio State University Comprehensive Cancer Center "“ Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC "“ James) and at University of Texas M.D. Anderson Cancer Center,...


Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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