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Latest Richard Pestell Stories

2013-11-29 14:40:55

Cyclin D1 controls cell cycle progression and microRNA biogenesis through Dicer -- a new mechanism promoting breast cancer Cyclin D1, a protein that helps push a replicating cell through the cell cycle also mediates the processing and generation of mature microRNA (miRNA), according to new research publishing November 29 in Nature Communications. The research suggests that a protein strongly implicated in human cancer also governs the non-protein-coding genome. The non-coding genome,...

2013-08-07 23:20:23

New study reveals molecular clues that may help physicians therapeutically target a highly aggressive form of breast cancer. (PRWEB) August 07, 2013 A study led by investigators from Thomas Jefferson University’s Kimmel Cancer Center has discovered molecular clues that may help physicians therapeutically target inflammatory breast cancer (IBC), a highly aggressive form of breast cancer. Their study, reported in the June 21 online issue of Breast Cancer Research and Treatment, identified...

2013-06-28 23:21:57

Recent studies by researchers at Thomas Jefferson University’s Kimmel Cancer Center have shown a gene known to coordinate initial development of the eye (EYA1) is a powerful breast tumor promoter in mice. The gene EYA1 was also shown to be overexpressed in a genetic breast cancer subtype called luminal B. Philadelphia, PA (PRWEB) June 28, 2013 Recent studies by researchers at Thomas Jefferson University’s Kimmel Cancer Center have shown a gene known to coordinate initial development...

2012-10-09 04:03:44

The Oncology Institute of Hope and Innovation welcomes Dr. Donald Paul Lombardi. Downey, California (PRWEB) October 08, 2012 Dr. Lombardi was born in Boston, MA and was the class Valedictorian at Wilmington High School. He majored in Biochemistry at Bowdoin College, graduating magna cum laude, and won a student summer research fellowship at Harvard Medical School. He received his M.D. at the University of Rochester School of Medicine and continued his summer research at Harvard. He...

2012-06-07 08:49:08

Study finds that HIV receptor CCR5 is induced by oncogenes in breast cancer cells, too The HIV drugs known as CCR5 antagonists may also help prevent aggressive breast cancers from metastasizing, researchers from the Kimmel Cancer Center at Jefferson suggest in a preclinical study published in a recent issue of Cancer Research. Such drugs target the HIV receptor CCR5, which the virus uses to enter and infect host cells, and has historically only been associated with expression in...

2012-05-19 23:13:33

For demonstrating great strength and dignity through a battle with brain cancer, Mr. Sabol will be honored with the Spirit of Courage Award. Philadelphia, PA (PRWEB) May 18, 2012 Jefferson´s Kimmel Cancer Center will host a tribute dinner to honor legendary filmmaker Steve Sabol, President of NFL Films, with the Spirit of Courage Award at the Union League of Philadelphia on June 5. The award is presented to an individual who has demonstrated great personal courage, strength and dignity...

2011-01-13 16:12:22

Researchers from the Kimmel Cancer Center at Jefferson and two other institutions have discovered new evidence that suggests the "longevity" protein SIRT1, known for its life-spanning effects in different species, can inhibit the development of a known precursor to prostate cancer, prostatic intraepithelial neoplasia (PIN). Results from the study could lead to new cancer prevention drugs that could not only block prostate cancer but promote longevity. The study, published in the February 1...

2010-12-15 15:04:40

Their animal study is the first to show that shutting down breast inflammation stops cancer onset and progression It took 12 years and a creation of a highly sophisticated transgenic mouse, but researchers at Kimmel Cancer Center at Jefferson have finally proven a long suspected theory: Inflammation in the breast is key to the development and progression of breast cancer. In the December 15 issue of Cancer Research, the scientists say they can now definitively show that an inflammatory...

2009-07-15 08:30:00

Researchers from the Kimmel Cancer Center at Jefferson have identified a protein relationship that may be an ideal treatment target for ER+ breast cancer. The study was reported in the July 15 issue of Cancer Research.DACH1, a cell fate determination factor protein, prevents cancer cell proliferation by repressing the function of estrogen receptorsï in breast cancer, the researchers found. However, they also found that as the presence of DACH1 decreases in breast cancer, the...

2005-08-01 16:24:11

PHILADELPHIA -- For about a decade, scientists have recognized that many cases of hereditary breast cancer result from a mutation of a specific gene called BRCA1, which, in its normal state, helps keep tumor formation in check. About five to 10 percent of breast cancer cases are linked to genetic miscues, about half of which are linked to BRCA1. But now scientists have discovered that a protein called cyclin D1, grossly overproduced in about half of all cases of breast cancer, can also...


Word of the Day
lambent
  • Licking.
  • Hence Running along or over a surface, as if in the act of licking; flowing over or along; lapping or bathing; softly bright; gleaming.
This word comes the Latin 'lambere,' to lick.
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