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Latest Rickets Stories

2010-03-29 16:00:00

MONTREAL, March 29 /PRNewswire/ -- Enobia Pharma Inc. unveiled findings from the first hypophosphatasia (HPP) self-reported patient survey intended to evaluate the burden of illness associated with HPP at the 2010 American College of Medical Genetics (ACMG) Annual Clinical Genetics Meeting. An update on the clinical program for ENB-0040, Enobia's investigational enzyme replacement therapy for HPP, was also presented at the meeting by Cheryl Rockman-Greenberg, MD, Medical Director, Child...

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2010-01-23 07:30:00

The growing number of hours children now spend indoors surfing the Web, watching television or playing video games may be linked to a resurgence of rickets, according to a new study published in the current issue of the British Medical Journal. Rickets is caused by chronic vitamin D deficiencies, which can result after long periods without natural sunlight or an inadequate diet. Children suffering from the bone-bending disease can develop painful and deformed bow-legs that do not properly...

2009-11-03 07:01:00

MONTREAL, Nov. 3 /PRNewswire/ -- Enobia Pharma announced today the initiation of a Phase 2 clinical study of ENB-0040, a bone-targeted enzyme replacement therapy, under investigation for the treatment of hypophosphatasia (HPP). The six-month study will assess the safety, efficacy and pharmacokinetics of ENB-0040 in up to 12 children with HPP. This study follows the recent presentation of positive Phase 2 data in infants, which showed that, in the majority of patients, six months of...

2009-10-27 08:33:52

Boston University School of Medicine researchers (BUSM) have found that 50,000 International Units (IU) of vitamin D2, given weekly for eight weeks, effectively treats vitamin D deficiency. Vitamin D2 is a mainstay for the prevention and treatment of vitamin D deficiency in children and adults. Continued treatment with the same dose of vitamin D2 every other week for up to six years after the initial eight-week period prevents vitamin D deficiency from recurring with no toxicity. The BUSM...

2009-10-26 16:11:47

National data suggest non-whites are especially at risk Millions of children in the United States between the ages of 1 and 11 may suffer from suboptimal levels of vitamin D, according to a large nationally representative study published in the November issue of Pediatrics, accompanied by an editorial. The study, led by Jonathan Mansbach, MD, at Children's Hospital Boston, is the most up-to-date analysis of vitamin D levels in U.S. children. It builds on the growing evidence that levels have...

2009-09-14 07:00:00

DENVER, Sept. 14 /PRNewswire/ -- Enobia Pharma today announced positive data from a clinical study of ENB-0040, a bone targeted enzyme replacement therapy, under investigation for the treatment of hypophosphatasia (HPP). After six months of treatment with ENB-0040, four of five severely affected patients showed marked improvements in bone mineralization, correction of skeletal defects, better respiratory function, including weaning from assisted ventilation, and cognitive and motor...

2009-09-08 07:00:00

MINNEAPOLIS, Sept. 8 /PRNewswire/ -- Nancy O'Dell, co-anchor of Access Hollywood, celebrity mom and author of the new parenting book Full of Life / Mom-to-Mom Tips I Wish Someone Had Told Me When I Was Pregnant, recognizes the importance of building and maintaining strong, healthy bones through a diet rich in calcium and vitamin D. Along with milk and cheese, enjoying a creamy cup of yogurt such as Yoplait(R) - the only leading brand of yogurt containing calcium and vitamin D in every...

2009-08-10 08:00:00

MONTREAL, Aug. 10 /PRNewswire/ -- Enobia Pharma, an emerging biotech company focused on developing novel therapeutics for serious bone disorders, today announced that it raised US$50 million from its current investors in a Series C financing. The proceeds will be used primarily to fund the ongoing development program for ENB-0040, Enobia's enzyme replacement therapy (ERT) for hypophosphatasia (HPP), a rare and potentially deadly genetic bone disorder for which there is no currently approved...

2009-06-30 14:08:10

A new report issued by the International Osteoporosis Foundation (IOF) and published in the scientific journal Osteoporosis International1, shows that populations across the globe are suffering from the impact of low levels of vitamin D. The problem is widespread and on the increase, with potentially severe repercussions for overall health and fracture rates.Compiled by IOF's expert working group on nutrition, the report reviews the scope and causes of low vitamin D levels in six regions:...

2009-05-18 08:30:00

HOUSTON, May 18 /PRNewswire-USNewswire/ -- Current recommendations for Vitamin D were called "grossly inadequate" today at the American Association of Clinical Endocrinologists (AACE) 18th Annual Meeting & Clinical Congress. (Logo: http://www.newscom.com/cgi-bin/prnh/20090324/DC88061LOGO-b) "National recommendations from the Food and Nutrition Board are 400 to 600 International Units (IU) a day," Neil Binkley, MD, an Associate Professor in Geriatrics and Endocrinology at the University...


Word of the Day
barratry
  • The offense of persistently instigating lawsuits, typically groundless ones.
  • An unlawful breach of duty on the part of a ship's master or crew resulting in injury to the ship's owner.
  • Sale or purchase of positions in church or state.
This word ultimately comes from the Old French word 'barater,' to cheat.
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