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Latest RNA polymerase Stories

How Genes Tell Cellular Construction Crews, 'Read Me Now!'
2013-08-13 12:52:34

Stowers Institute for Medical Research Stowers researchers show that DNA sequences at the beginning of genes -- at least in fruit flies -- contain more information than previously thought When egg and sperm combine, the new embryo bustles with activity. Its cells multiply so rapidly they largely ignore their DNA, other than to copy it and to read just a few essential genes. The embryonic cells mainly rely on molecular instructions placed in the egg by its mother in the form of RNA....

2013-07-10 19:45:13

First-ever compendium of RNA sequences will be important guide to understanding the root of genetic diseases Every cell in an organism's body has the same copy of DNA, yet different cells do different things; for example, some function as brain cells, while others form muscle tissue. How can the same DNA make different things happen? A major step forward is being announced today that has implications for our understanding of many genetically-linked diseases, such as autism. Scientists...

Junk DNA Vital Biological Role
2013-06-27 08:25:25

Rebekah Eliason for redOrbit.com - Your Universe Online At the center of most human cells, genomic DNA lies tucked away within a nucleus. However, a surprisingly small percentage of this DNA actually codes for genes that can be translated into proteins. In fact, some researchers estimate as much as 98 percent of this DNA seems to have a puzzling lack of purpose, leading many to refer to it as 'junk DNA.' However, a new study from UC San Francisco now emphasizes the potentially important...

2013-05-16 23:32:20

The novel Natural Sciences Bibliographic Web Portal aims to provide comprehensive bibliographic information on the basic and applied life, earth and health sciences and has published over 184,800 references and 133,600 tags. Scien.net has now newly included the category Polymerase which is an enzyme associated with polymers of nucleic acids such as the deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), and on Reductase, which is an enzyme that is known for catalyzing reduction and...

2012-09-03 11:23:39

DEAD-box proteins function as recycling nanopistons when unwinding RNA Molecular biologists at The University of Texas at Austin have solved one of the mysteries of how double-stranded RNA is remodeled inside cells in both their normal and disease states. The discovery may have implications for treating cancer and viruses in humans. The research, which was published this week in Nature, found that DEAD-box proteins, which are ancient enzymes found in all forms of life, function as...

2012-07-20 01:50:16

New research has shown that a protein does something that scientists once thought impossible: It unfolds itself and refolds into a completely new shape. This protein, called RfaH, activates genes that allow bacterial cells to launch a successful attack on their host, causing disease. The researchers determined that RfaH starts out in its alpha form, composed of two spiral shapes. Later, in its beta form, it resembles spokes on a wheel and is called a barrel. When RfaH refolds, it...

2012-03-02 01:36:29

For the last dozen years, scientists have known that minuscule strings of genetic material called small RNA are critically important to our genetic makeup. But finding out what they do hasn´t been easy. Now a scientist from Michigan Technological University and his team have developed a way to turn off small RNAs and find out just how important they can be. When it comes to inheritance, DNA is just the half of it. What we are is also driven by the epigenetic world of RNA: the...

2012-01-26 14:58:18

The discovery made by Dr. François Robert's team confirms the universality of an essential cellular process Dr. François Robert, molecular biology researcher at the Institut de recherches cliniques de Montréal (IRCM), and his team confirmed that the phosphorylation of RNA polymerase II, a key enzyme in the process of gene expression, is uniform across all genes. This discovery, which contributes to numerous debates on the topic within the scientific...

2011-12-22 15:35:16

Transcriptional elongation control takes on new dimensions as Stowers researchers find gene class-specific elongation factors Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in the process that copies the information encoded in our DNA into protein-making instructions carried by messenger RNA. In a new report appearing in the Dec. 23,...

2011-07-15 14:16:31

Successful gene expression requires the concerted action of a host of regulatory factors. Long overshadowed by bonafide transcription factors, coactivators"”the hanger-ons that facilitate transcription by docking onto transcription factors or modifying chromatin"”have recently come to the fore. In their latest study, published in the July 15, 2011, issue of Genes & Development, researchers at the Stowers Institute for Medical Research discovered that the highly conserved...