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Latest RNA-Seq Stories

2012-02-14 14:21:41

GW Cancer Research Team in the Department of Biochemistry and Molecular Biology, in the School of Medicine and Health Sciences, published a study that is the first of its kind to use mRNA sequencing to look at the expression of genome, at a unprecedented resolution  at the current time, in three types of breast cancer. The study titled, “Transcriptomic landscape of breast cancer through mRNA sequencing,” is published in the Feb. 14 edition of the journal, Scientific Reports,...

2012-02-13 23:24:41

New software key for personalized cancer medicine High-throughput DNA sequencing technologies are leading to a revolution in how clinicians diagnose and treat cancer. The molecular profiles of individual tumors are beginning to be used in the design of chemotherapeutic programs optimized for the treatment of individual patients. The real revolution, however, is coming with the emerging capability to inexpensively and accurately sequence the entire genome of cancers, allowing for the...

2012-02-13 14:55:25

Study published in the journal Nature Biotechnology In a new study published online in Nature Biotechnology, researchers from BGI, the world's largest genomics organization, reported the evidence of extensive RNA editing in a human cell line by analysis of RNA-seq data, demonstrating the need for new robust methods to identify important post-transcriptional editing events. RNA editing is a normal but not yet fully understood process in which small nucleotide changes occur after DNA has...

2012-01-31 10:19:57

Researchers at the RIKEN Omics Science Center (OSC) have developed a robotic workflow for sample preparation on the HeliScope single molecule sequencer which drastically reduces sample preparation time to from 42 days to only 8 days. The workflow uses Cap Analysis of Gene Expression (CAGE), a unique method developed at the OSC for determining transcriptional starting sites in the genome and their expression levels. A key obstacle in DNA sequencing is the long time required for sample...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.