Latest RNA splicing Stories
Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing â€“ a critical step in the earliest stage of protein production.
In a discovery that has implications for developing treatments against cancer and potentially deadly viruses, researchers at SUNY Downstate Medical Center have discovered the function of proteins that can enhance the progression of certain viruses and cancer cells.
The devastating, currently incurable motor-neuron disease spinal muscular atrophy (SMA) might soon be treated with tiny, chemically modified pieces of RNA called antisense oligonucleotides (ASOs).
A bacteria that lives in hot springs in Japan may help solve one of the mysteries of the early evolution of complex organisms.
A rose by any other name may smell as sweet, but it would no longer be a rose. If a grass is booted out of the grass family, where does it go?
SAN DIEGO, March 22 /PRNewswire/ -- OFC/NFOEC 2010, Booth 1023 - OFS today announces the commercial release of its active clad alignment FITELÂ® S153A hand-held fusion splicer to the North American market at the industry's premier annual conference, OFC/NFOEC in San Diego, California March 21-25, 2010. "The key advantage of the FITEL S153A splicer is that it helps to achieve lower splicing loss with less user skills required as compared to a conventional fixed v-groove clad alignment fusion...
Using a new approach to studying the spliceosome, a team led by University of Michigan chemistry and biophysics professor Nils Walter, collaborating closely with a team led by internationally recognized splicing experts John Abelson and Christine Guthrie of the University of California, San Francisco, spied on the splicing process in single molecules.
Now researchers at the Stanford University School of Medicine have shown that this tuning process is accomplished in part by restricting the number of messages, called transcripts, produced from each gene.
A novel finding, described today (Feb. 4) on the Science Express Web site by teams from the National Cancer Institute, The University of Texas Health Science Center at San Antonio and the University of Toronto, offers a clue as to how genes can have what you might call multiple personalities.
Research on the genetic defect that causes myotonic muscular dystrophy has revealed that the mutation disrupts an array of metabolic pathways in muscle cells through its effects on two key proteins.
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