Latest RNA Stories
The novel Natural Sciences Bibliographic Web Portal aims to provide comprehensive bibliographic information on the basic and applied life, earth and health sciences and has published over 184,800 references and 133,600 tags. Scien.net has now newly included the category Polymerase which is an enzyme associated with polymers of nucleic acids such as the deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), and on Reductase, which is an enzyme that is known for catalyzing reduction and...
Animals, insects, and plants use a variety of sensing mechanisms to detect invading pathogens such as viruses. One complex and effective antiviral defense system they share is based on recognition of double-stranded RNA (dsRNA), often produced when a virus invades a host cell. New information leading to a clearer understanding of the mechanisms underlying viral dsRNA sensing is presented in a comprehensive Review article published in Journal of Interferon & Cytokine Research, a...
MOUNTAIN VIEW, Calif., May 1, 2013 /PRNewswire/ -- Clontech Laboratories, Inc., a wholly-owned subsidiary of Takara Bio Inc., today announced the release of the SMARTer Universal Low Input RNA Kit for Sequencing. The SMARTer Universal Low Input RNA Kit extends Clontech's NGS (Next Generation Sequencing) solutions to include low input samples of compromised RNA. It combines Clontech's patented SMART(TM) (Switching Mechanism at 5' End of RNA Template) technology for ds cDNA synthesis...
HZI researchers discover multiple versions of microbial defense genes that lend themselves to being exploited by biotechnology Even bacteria have a kind of “immune system” they use to defend themselves against unwanted intruders – in their case, viruses. Scientists at the Helmholtz Center for Infection Research (HZI) in Braunschweig, Germany, were now able to show that this defense system is much more diverse than previously thought and that it comes in multiple versions. Their goal...
Proteins, the workhorses of the body, can have more than one function, but they often need to be very specific in their action or they create cellular havoc, possibly leading to disease. Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered how an enzyme co-factor can bestow specificity on a class of proteins with otherwise nonspecific biochemical activity. The protein in question helps in the assembly of ribosomes, large macromolecular machines that...
-Determining a breast-cancer patient’s prognosis can be difficult because breast tumors contain many genetic differences and there are many subtypes; -This study combined and analyzed large masses of data from 466 cases of the most common type of breast cancer; -The study identified a small group of molecules that might predict breast-cancer prognosis across many subtypes of the disease and at its early stages; -For the first time a prognostic signature in cancer is composed of both mRNA...
JUPITER, Fla., April 30, 2013 /PRNewswire/ -- SMaRT Therapeutics, Inc., a leading biotechnology company focused on the development of small-molecule drugs that target and modulate RNA, announced the appointment of Dr. John H. Abeles to its Advisory Board. Dr. Abeles has had a long and distinguished career in the biotechnology and pharmaceutical industries. He practiced medicine in London before serving as a Senior Medical Executive with Sterling Drug, Pfizer and Revlon Healthcare....
Altogen Labs is a GLP compliant laboratory that provides preclinical research and biology contract research services (CRO). Altogen Labs now offers wide variety of preclinical CRO services, including drug development, generation of stable cell lines, RNAi gene silencing and in vivo research services (xenograft, in vivo siRNA delivery), pharm/tox assays (IC50), cell banking, and ELISA assay development. Austin, TX (PRWEB) April 26, 2013 Altogen Labs, a biotechnology company focused on...
A new level of variation in messenger RNAs exposed Like musicians in an orchestra who have the same musical score but start and finish playing at different intervals, cells with the same genes start and finish transcribing them at different points in the genome. For the first time, researchers at EMBL have described the striking diversity of messenger RNAs (mRNAs) that such start and end variation produces, even from the simple genome of yeast cells. Their findings, published today in...
Researchers at the University of Bonn decode a kind of trigger switch for the conversion of fat cells For a long time, scientists have dreamt of converting undesirable white fat cells into brown fat cells and thus simply have excess pounds melt away. Researchers at the University of Bonn have now gotten a step closer to this goal: They decoded a "toggle switch" in mice which can significantly stimulate fat burning. The results are now being presented in the scientifc journal "Nature...
Latest RNA Reference Libraries
Caenorhabditis elegans is a species of parasitic roundworm in the Nematoda phylum. It can be found in temperate regions, in many different areas of the world. It prefers to reside in nutrient rich soils. Its scientific name is derived from the Greek terms Caeno, meaning recent, rhabditis, meaning rod-like, and the Latin term elegans, which means elegant. It was first named by Maupas in 1900, but was not classified in the Caenorhabditis subgenus until 1952 by Osche. Caenorhabditis elegans...
The Proceedings of the National Academy of Sciences of the United States of America (PNAS) is a peer-reviewed scientific journal established in 1914 as the official journal of the US National Academy of Sciences. The first managing editor of the journal was mathematician Edwin Bidwell Wilson. As of May 2012, the editor-in-chief is Inder M. Verma. PNAS is published weekly in print, and daily online in PNAS Early Edition. The first issue of PNAS was published in 1915, and the journal...
The Biophysical Journal is a peer-reviewed scientific journal published biweekly by Cell Press on behalf of the Biophysical Society. It was established in 1960. The editor-in-chief is Edward Egelman. It covers all aspects of biophysics. It is the leading international journal for original research in molecular, cellular, and system biophysics. Modern biophysics is a broad and rapidly advancing field encompassing the study of biological structures with a focus on mechanisms at the...
