Latest RNA Stories
As scientists continue to unravel the complexity of the human genome and to uncover vital elements that play a role in both normal physiology and disease, one particular class of elements called noncoding RNAs is gaining a lot of attention. Guest Editor Tom Cech, PhD and Executive Editor Fintan Steele, PhD explore the enormous potential value of this rapidly advancing research area in their Editorial " The (Noncoding) RNA World." The authors introduce a special research section on noncoding...
PHILADELPHIA and REHOVOT, Israel, Feb. 14, 2013 /PRNewswire/ -- Rosetta Genomics Ltd. (NASDAQ: ROSG), a leading developer and provider of microRNA-based molecular diagnostics, today announced that the Company has received two notices of allowance from the U.S. Patent and Trademark Office ("USPTO") for Patent Applications 12/661,041 and 12/850,091. The allowed claims of 12/661,041, entitled "microRNAs and Uses Thereof," cover the composition of matter for miR-29c*, as well as...
ST. LOUIS, Feb. 13, 2013 /PRNewswire/ -- Sigma-Aldrich((R)) Corporation (NASDAQ: SIAL) today announced that Sigma Life Science, its innovative biological products and services business, through an exclusive collaboration with Drs. Hideo Iba and Takeshi Haraguchi at the University of Tokyo, released MISSION((R) )Synthetic and Lentiviral microRNA Inhibitors based upon the Tough Decoy (TuD) design for the long-term suppression of any miRNA endogenous to humans or mice. Custom designs for...
Ability to tune gene activity will permit refined research for drug resistance, cancer Scientists who built a synthetic gene circuit that allowed for the precise tuning of a gene's expression in yeast have now refined this new research tool to work in human cells, according to research published online in Nature Communications. "Using this circuit, you can turn a gene from completely off to completely on and anywhere between those two extremes in each cell at once. It's a nice tool if...
Research by UC Riverside plant pathologists is the first to show that RNA silencing regulates plant defense against the notorious Phytophthora pathogens When a pathogen attacks a plant, infection usually follows after the plant’s immune system is compromised. A team of researchers at the University of California, Riverside focused on Phytophthora, the pathogen that triggered the Irish Famine of the 19th century, and deciphered how it succeeded in crippling the potato plant’s immune...
PHILADELPHIA and REHOVOT, Israel, Feb. 7, 2013 /PRNewswire/ -- Rosetta Genomics Ltd. (NASDAQ: ROSG), a leading developer and provider of microRNA-based molecular diagnostics, today announced that data from a study demonstrating the ability of microRNA expression to serve as a biomarker to predict the progression of bladder urothelial carcinoma were published online in the British Journal of Urology International, in an article entitled, "Predicting progression of bladder...
CAMBRIDGE, England, Jan. 31, 2013 /PRNewswire/ -- One of the most innovative biotechnologies of the last decade has recently been developed. SINEUP allows scientists, for the first time, to target individual genes in cells to knockup, or increase, the amount of protein they make. The technique will improve Protein manufacture, analyse the function of genes and engineer improved cell function. This novel technology is based on pioneering research in the lab of Dr Stefano...
Non-coding RNA is essential for normal embryonic cardiogenesis Many different tissues and organs form from pluripotent stem cells during embryonic development. To date it had been known that these processes are controlled by transcription factors for specific tissues. Scientists from the Max Planck Institute for Molecular Genetics in Berlin, in collaboration with colleagues at MIT and the Broad Institute in Boston, have now been able to demonstrate that RNA molecules, which do not act as...
U-M researchers develop method that could enhance gene sequencing data When researchers sequence the RNA of cancer cells, they can compare it to normal cells and see where there is more RNA. That can help lead them to the gene or protein that might be triggering the cancer. But other than spotting a few known instigators, what does it mean? Is there more RNA because it’s synthesizing too quickly or because it’s not degrading fast enough? What part of the biological equilibrium is...
Monsanto to evaluate PhaseRx's SMARTT Polymer Technology® for potential agricultural applications. Seattle, WA. (PRWEB) January 24, 2013 PhaseRx, Inc., a privately held RNAi delivery technology company, announced today that it has signed a funded technology evaluation agreement with Monsanto Company for PhaseRx's delivery technologies. Through the agreement, Monsanto will evaluate PhaseRx's SMARTT Polymer Technology® for potential agricultural applications. Terms of...
Latest RNA Reference Libraries
DNA probes help scientists to detect a specific gene in a long DNA sequence. According to Dr. Michael A. Pfaller, DNA probes are “single-stranded pieces of nucleic acid, labeled with a specific tracer (isotope, enzyme, or chromophore), that will hydrogen bond (hybridize) with complementary single-stranded pieces of DNA (or RNA) under the appropriate conditions of pH, temperature, and iconic strength.” The Foundation for Genomics and Population Health website has a helpful video about...
The activity of any living cell, and by extension life itself, depends on protein synthesis and the transcription of DNA. If proteins are the machinery of cellular function, then DNA are the machine assembly lines – responsible for accurately and efficiently ‘transcribing’ protein messengers, structures and enzymes. DNA transcription begins in the nucleus of a cell when an enzyme called RNA polymerase binds to the DNA strand. Sequences within the DNA direct the polymerase to...
Caenorhabditis elegans is a species of parasitic roundworm in the Nematoda phylum. It can be found in temperate regions, in many different areas of the world. It prefers to reside in nutrient rich soils. Its scientific name is derived from the Greek terms Caeno, meaning recent, rhabditis, meaning rod-like, and the Latin term elegans, which means elegant. It was first named by Maupas in 1900, but was not classified in the Caenorhabditis subgenus until 1952 by Osche. Caenorhabditis elegans...
The Proceedings of the National Academy of Sciences of the United States of America (PNAS) is a peer-reviewed scientific journal established in 1914 as the official journal of the US National Academy of Sciences. The first managing editor of the journal was mathematician Edwin Bidwell Wilson. As of May 2012, the editor-in-chief is Inder M. Verma. PNAS is published weekly in print, and daily online in PNAS Early Edition. The first issue of PNAS was published in 1915, and the journal...
The Biophysical Journal is a peer-reviewed scientific journal published biweekly by Cell Press on behalf of the Biophysical Society. It was established in 1960. The editor-in-chief is Edward Egelman. It covers all aspects of biophysics. It is the leading international journal for original research in molecular, cellular, and system biophysics. Modern biophysics is a broad and rapidly advancing field encompassing the study of biological structures with a focus on mechanisms at the...
