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Latest RNA Stories

2014-05-27 11:46:17

University of Bristol An international team of scientists has made a major step forward in our understanding of how enzymes 'edit' genes, paving the way for correcting genetic diseases in patients. Researchers at the Universities of Bristol, Münster and the Lithuanian Institute of Biotechnology have observed the process by which a class of enzymes called CRISPR – pronounced 'crisper' – bind and alter the structure of DNA. The results, published in the Proceedings of the National...

2014-05-27 08:28:04

MARLBOROUGH, Mass., May 27, 2014 /PRNewswire/ -- RXi Pharmaceuticals Corporation (NASDAQ: RXII), a biotechnology company focused on discovering, developing and commercializing innovative therapies addressing major unmet medical needs using RNA-targeted technologies, today announced that the Company's President & CEO, Dr. Geert Cauwenbergh, will present at the Jefferies 2014 Global Healthcare Conference on Tuesday, June 3, 2014 at 8:00 a.m. EDT. Dr. Cauwenbergh will discuss the...

Relaxation Helps Pack DNA More Easily Into A Virus
2014-05-27 03:52:42

University of California - San Diego Researchers at the University of California, San Diego have found that DNA packs more easily into the tight confines of a virus when given a chance to relax, they report in a pair of papers to be published in in the early edition of the Proceedings of the National Academy of Sciences the week of May 26 and the May 30 issue of Physical Review Letters. DNA is a long, unwieldy molecule that tends to repel itself because it is negatively charged, yet it...

2014-05-22 08:29:07

WESTBOROUGH, Mass., May 22, 2014 /PRNewswire/ -- RXi Pharmaceuticals Corporation (NASDAQ: RXII), a biotechnology company focused on discovering, developing and commercializing innovative therapies addressing major unmet medical needs using RNA-targeted technologies, today announced that it received the Notice of Allowance from the United States Patent and Trademark Office on its novel, self-delivering RNAi platform (sd?rxRNA®). The patent, titled "Reduced Size Self-Delivering RNAi...

2014-05-14 23:02:07

The new NextGEN™ CRISPR genome engineering tools and services provided by Transposagen are ideal when research and drug discovery applications require clean, high-precision genome editing. Lexington, KY (PRWEB) May 14, 2014 Altering the genome with targeted nucleases is powerful and increasingly necessary for research and drug discovery. The CRISPR-Cas9 system has gained popularity due to its simplicity and high efficiency. While the original CRISPR technology is not owned or...

2014-05-13 08:31:03

- Greater than 100-fold Allele-specific silencing of V30M variant for the treatment of Familial Amyloid Polyneuropathy (TTR-FAP) - SAN DIEGO, May 13, 2014 /PRNewswire/ -- Arcturus Therapeutics, Inc., a leading RNA medicines company pursuing rare diseases, today announced the nomination of its second pipeline program targeting the TTR V30M variant using UNA(TM)-mediated RNAi allele-specific silencing for the treatment of TTR-mediated familial amyloid polyneuropathy (FAP). Additional...

2014-05-11 00:21:06

The NextGEN(TM) CRISPR genome engineering tools and services provided by Transposagen are ideal when research and drug discovery applications require clean, high-precision genome editing. LEXINGTON, Ky., May 11, 2014 /PRNewswire-iReach/ -- Altering the genome with targeted nucleases is powerful and increasingly necessary for research and drug discovery. The CRISPR-Cas9 system has gained popularity due to its simplicity and high efficiency. While the original CRISPR technology is not...

2014-05-09 16:24:39

LA JOLLA, Calif., May 9, 2014 /PRNewswire/ -- Regulus Therapeutics Inc. (NASDAQ: RGLS), a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today announced that Neil W. Gibson, Ph.D., Chief Scientific Officer of Regulus, will present a company overview at the Bank of America Merrill Lynch 2014 Healthcare Conference on Thursday, May 15, 2014 at 12:00 p.m. PDT. The conference is being held at the Encore at the Wynn Las Vegas....

2014-05-08 16:27:14

- 'Clinical Map Initiative' On Track; Advanced RG-101 and RG-012, Expect to Nominate Third microRNA Clinical Candidate by YE 2014 - LA JOLLA, Calif., May 8, 2014 /PRNewswire/ -- Regulus Therapeutics Inc. (NASDAQ:RGLS), a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today reported financial results and highlights for the quarter ended March 31, 2014 and provided a summary of recent corporate highlights. "In the first quarter of...

Genetically Altering E. Coli With New Semi-Synthetic DNA Base Pairs
2014-05-08 07:24:29

Lawrence LeBlond for redOrbit.com - Your Universe Online It is well-known that all life on Earth is made up of two base pairs, known as A-T (adenine–thymine) and C-G (cytosine–guanine), which form the standard double helix DNA strand. But that could all change now that researchers at The Scripps Research Institute (TSRI) have engineered a bacterium to contain an extra pair of DNA “letters” that are not found anywhere else in nature. The cells of this bacterium are also able to...


Latest RNA Reference Libraries

Brief Introduction To DNA Probes
2014-01-12 00:00:00

DNA probes help scientists to detect a specific gene in a long DNA sequence. According to Dr. Michael A. Pfaller, DNA probes are “single-stranded pieces of nucleic acid, labeled with a specific tracer (isotope, enzyme, or chromophore), that will hydrogen bond (hybridize) with complementary single-stranded pieces of DNA (or RNA) under the appropriate conditions of pH, temperature, and iconic strength.” The Foundation for Genomics and Population Health website has a helpful video about...

Caenorhabditis elegans
2014-01-12 00:00:00

Caenorhabditis elegans is a species of parasitic roundworm in the Nematoda phylum. It can be found in temperate regions, in many different areas of the world. It prefers to reside in nutrient rich soils. Its scientific name is derived from the Greek terms Caeno, meaning recent, rhabditis, meaning rod-like, and the Latin term elegans, which means elegant. It was first named by Maupas in 1900, but was not classified in the Caenorhabditis subgenus until 1952 by Osche. Caenorhabditis elegans...

Proceedings of the National Academy of Sciences
2012-05-29 11:19:42

The Proceedings of the National Academy of Sciences of the United States of America (PNAS) is a peer-reviewed scientific journal established in 1914 as the official journal of the US National Academy of Sciences. The first managing editor of the journal was mathematician Edwin Bidwell Wilson. As of May 2012, the editor-in-chief is Inder M. Verma. PNAS is published weekly in print, and daily online in PNAS Early Edition. The first issue of PNAS was published in 1915, and the journal...

Biophysical Journal
2012-05-28 10:08:02

The Biophysical Journal is a peer-reviewed scientific journal published biweekly by Cell Press on behalf of the Biophysical Society. It was established in 1960. The editor-in-chief is Edward Egelman. It covers all aspects of biophysics.  It is the leading international journal for original research in molecular, cellular, and system biophysics. Modern biophysics is a broad and rapidly advancing field encompassing the study of biological structures with a focus on mechanisms at the...

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Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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