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Latest Rockefeller University Stories

2011-06-13 23:01:00

PHILADELPHIA, June 14, 2011 /PRNewswire-USNewswire/ -- The Pew Charitable Trusts named 10 outstanding early-career scientists to be Pew Latin American Fellows in the Biomedical Sciences. By providing these individuals with an opportunity to further their research, advance scientific knowledge, and collaborate with investigators in the U.S., the program aims to build scientific capability throughout the region. This prestigious program provides $60,000 in salary support over two years for...

2011-06-08 21:51:42

Scientists at Rockefeller University and The Scripps Research Institute have developed the first genetically humanized mouse model for hepatitis C, an achievement that will enable researchers to test molecules that block entry of the hepatitis C virus into cells as well as potential vaccine candidates. The finding is reported in the June 9 issue of the journal Nature. While the hepatitis C virus can infect chimpanzees and humans, scientists have been unable to study the progression of the...

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2011-06-06 14:04:16

Forests in many regions are becoming larger carbon sinks thanks to higher density, U.S. and European researchers say in a new report. In Europe and North America, increased density significantly raised carbon storage despite little or no expansion of forest area, according to the study, led by Aapo Rautiainen of the University of Helsinki, Finland, and published in the online, open-access journal PLoS One. Even in the South American nations studied, more density helped maintain regional...

2011-06-02 09:00:00

NEW YORK, June 2, 2011 /PRNewswire/ -- Over 1000 guests will pack New York's American Museum of Natural History tonight to honor David W. Levinson, Chairman and CEO of L&L Holding Company. The "Sold Out" event benefits the Jeffrey Modell Foundation (JMF), which is celebrating 25 years of research and patient support dedicated to Primary Immunodeficiency (PI). To view the multimedia assets associated with this release, please click...

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2011-04-26 06:35:00

A recent US study suggests that aspirin and other anti-inflammatory drugs, including ibuprofen and naproxen, may reduce the effectiveness of the most widely used anti-depressant medications -- selective serotonin reuptake inhibitors (SSRIs), reports AFP. The finding, published this week in the online issue of the Proceedings of the National Academy of Sciences, may explain why many depressed patients taking SSRIs do not respond to antidepressant treatment. Scientists at the Fisher Center...

2011-04-25 16:38:32

Scientists at the Fisher Center for Alzheimer's Disease Research at The Rockefeller University, led by Paul Greengard, Ph.D., and Jennifer Warner-Schmidt, Ph.D., have shown that anti-inflammatory drugs, which include ibuprofen, aspirin and naproxen, reduce the effectiveness of the most widely used class of antidepressant medications, the selective serotonin reuptake inhibitors, or SSRIs, taken for depression and obsessive-compulsive disorder and anxiety disorders. This surprising discovery,...

2011-04-18 13:27:07

Whether you're talking about genes, or neurons, or the workings of a virus, at the most fundamental level, biology is a matter of proteins. So understanding what protein complexes look like and how they operate is the key to figuring out what makes cells tick. By harnessing the unique properties of polarized light, Rockefeller scientists have now developed a new technique that can help deduce the orientation of specific proteins within the cell. By turning their instruments toward the nuclear...

2011-04-11 15:43:42

When viruses attack, one molecule more than any other fights back. Interferon triggers the activation of more than 350 genes, and despite the obvious connection, the vast majority have never been tested for antiviral properties. A team of researchers, led by scientists from Rockefeller University, for the first time has carried out a comprehensive, systematic evaluation of the antiviral activity of interferon-induced factors. The findings, published online today in the journal Nature, are a...

2011-03-16 18:30:21

Cells, which employ a process called autophagy to clean up and reuse protein debris leftover from biological processes, were the original recyclers. A team of scientists from Paul Greengard's Rockefeller University laboratory have linked a molecule that stimulates autophagy with the reduction of one of Alzheimer's disease's major hallmarks, amyloid peptide. Their finding suggests a mechanism that could be used to eliminate built-up proteins in diseases such as Alzheimer's, Down syndrome,...

2010-11-10 13:56:14

Dendritic cells, known to be the prime movers of the body's immune response, are still notoriously difficult to study in humans. Samples, which come primarily from bone marrow or lymphoid tissue, are simply too difficult to obtain. But new research at Rockefeller University has shown scientists a way to study "authentic" dendritic cells from mouse monocytes, which are abundant in the blood, a much more accessible source in humans. The discovery, published last week in Cell, promises to...