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2009-02-19 14:31:06

A new formula that involves gene testing could equip doctors with a better means of gauging the dosage of the common blood-thinning drug warfarin, according to a new large-scale study. Warfarin is one of the most widely prescribed drugs in the world "“ an estimated 2 million Americans with heart conditions or other risk factors begin taking the drug each year "“ but doctors currently use a method of trial and error to determine how much a patient should be taking. This method...

2009-01-20 10:07:10

New analyses led by the University of Cincinnati (UC) show that genetic testing used to guide initial dosing of the blood-thinner warfarin may not be cost-effective for typical patients with atrial fibrillation but may be for patients at higher risk for major bleeding. This study is being published in the Jan. 20, 2009, edition of Annals of Internal Medicine. Warfarin is commonly prescribed to prevent blood clotting, particularly for patients with atrial fibrillation"”a type of abnormal...

2008-12-22 11:25:36

Researchers from Boston University School of Medicine (BUSM) have determined the optimal dose-management strategy to derive maximal benefit from warfarin therapy and improve patient outcomes. Results of the study appear online in the December 2008 issue of the Journal of Thrombosis and Haemostasis. Warfarin is highly effective to prevent strokes, treat venous thromboembolism and for other conditions. Numerous studies have focused on the underutilization of warfarin for patients with atrial...

2008-11-03 09:00:39

ARYx Therapeutics Inc. (NASDAQ:ARYX), a biopharmaceutical company, today announced it has completed enrollment in EmbraceAC, a Phase 2/3 double-blind clinical trial comparing its oral anticoagulation therapy, ATI-5923, against the leading anticoagulant agent, warfarin. The purpose of the trial is to evaluate whether ATI-5923 is superior to warfarin in its ability to maintain patients within a target therapeutic range of the level of anticoagulation as measured by INR (International Normalized...

2008-10-30 09:00:40

SeraCare Life Sciences, Inc. (NASDAQ: SRLS) launched the Company's anticipated genetic controls business with the introduction of two new products at the Association for Molecular Pathology 2008 Annual Meeting. Initial products launched include ACCURUN(R) 601 controls for diagnostic testing of warfarin sensitivity and ACCURUN(R) 610 controls for thrombophilia testing, which were developed internally by SeraCare. Additionally, the Company announced that it has entered into an exclusive...

2008-10-28 12:30:00

U.S. scientists say they're using DNA extracted from saliva to customize prescriptions and solve dosing problems that often confound doctors and patients. By using DNA to customize a prescription, researchers at Temple University's School of Pharmacy hope to prevent adverse drug reactions. At the top of the list of problem drugs is warfarin (Coumadin), the most widely prescribed anticoagulant. The researchers say they're trying to find the correlation between genotypes and the correct...

2008-10-27 18:00:10

Proper instructions of how to take the blood thinning drug warfarin resulted in less risk of bleeding complications, U.S. researchers said. The University of Pennsylvania School of Medicine study, published in the Journal of General Internal Medicine, also indicated patients who see only one physician and fill their prescription at a single pharmacy were 60 percent less likely to experience serious bleeding events. The researchers theorize that improved patient communication -- which...

2008-09-30 16:00:00

People who take the blood thinning drug warfarin may have larger amounts of bleeding in the brain and increased risk of death, U.S. researchers said. Study author Dr. Matthew L. Flaherty of the University of Cincinnati said warfarin is commonly prescribed to prevent blood clotting to prevent heart attacks. Studies have shown it helps prevent ischemic stroke for patients with an abnormal heart rhythm called atrial fibrillation. However, if the drug makes the blood too thin, it can increase...

2008-09-05 06:00:23

Inverness Medical Physician Diagnostics Group, a division of Inverness Medical Innovations, today announced the launch of the INRatio(R)2 PT/INR Monitoring System, a portable device that measures blood-clotting time, also known as prothrombin time, using one drop of blood from a patient's finger. The INRatio2 is used by healthcare professionals and their patients in the management of warfarin, a blood-thinning drug, to monitor the effectiveness of the drug and warn of potential blood clots...

2008-07-31 12:01:05

Speaking at the American Association for Clinical Chemistry (AACC) 2008 Conference and Exhibition in Washington, DC, James White, Chief Executive, Osmetech plc (LSE:OMH), confirmed that following receipt of its 510(k) clearance last week from the US Food & Drug Administration ('FDA'), the Company has now commenced shipments of its second generation eSensor(R) XT-8 molecular diagnostics platform and Warfarin Sensitivity Test. Mr White said: "We are delighted with the initial response...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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