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Latest Rofecoxib Stories

2009-11-23 16:57:24

Clinical trial data indicated an association between the anti-inflammatory medication rofecoxib and cardiovascular risk as early as December 2000, before the product was taken off the market in September 2004, according to a report in the November 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. Rofecoxib was introduced to the market in May 1999 and quickly became a commercial success, with sales reaching $2 billion annually, according to background information in...

2009-11-23 16:34:15

Provides lessons for post-market pharmaceutical safety Evidence of cardiovascular risks associated with taking Vioxx, the popular, nonsteroidal anti-inflammatory drug (rofecoxib), could have been identified nearly four years before its manufacturer, Merck & Co. Inc., voluntarily pulled the drug from the market. Led by Joseph Ross, MD, MHS, Assistant Professor of Geriatrics and Palliative Medicine and of Medicine at Mount Sinai School of Medicine, a team of six investigators analyzed 30...

2009-11-13 12:11:00

ENGLEWOOD, Colo., Nov. 13 /PRNewswire/ -- On November 10, 2009, Judge David R. Herndon, the federal judge presiding over the Yasmin and Yaz (Drospirenone) Marketing Sales Practices and Product Liability Multidistrict Litigation MDL #2100 in the Southern District of Illinois, appointed Michael S. Burg as one of three Co-Lead Counsel to serve on the Plaintiffs' Steering Committee. The PSC reports directly to Judge Herndon, and is responsible for conducting pre-trial proceedings on behalf of...

2009-10-07 14:18:00

NEW YORK, Oct. 7 /PRNewswire/ -- Reflecting another strong year of major trial wins, multi-million dollar settlements and key leadership appointments in a variety of complex litigation matters, the firm of Seeger Weiss LLP has once again been named to the National Law Journal's Plaintiffs Hot List. This is the third straight year that the New York-based firm, now with 36 lawyers in five offices, has been included among the NLJ's selection of the country's top plaintiffs' counsel...

2009-06-23 09:52:56

A study published this week in the open access journal PLoS Medicine shows that for elderly people at risk of cardiovascular disease, the presence of inflammatory markers in the blood can identify that an individual is at a higher risk of a fatal rather than a non-fatal heart attack or stroke.Inflammation is an immune response to injury. However, inflammation is also thought to play a role in cardiovascular disease. Previous studies have shown an association between high levels of markers of...

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2009-06-13 13:50:01

Federal regulators said on Friday new labels on popular asthma drugs like Merck's Singulair must highlight language about suicidal behavior, depression and anxiety seen in a small number of patients, The Associated Press. The Food and Drug Administration said after 15 months of investigation that drug companies Merck & Co. Inc., AstraZeneca and Cornerstone Therapeutics would have to raise label warnings about psychiatric problems reported by a handful of patients that were prescribed the...

2009-05-13 11:32:33

An analysis of previous studies indicates that among patients with peripheral artery disease, aspirin use is associated with a statistically nonsignificant decrease in the risk of a group of combined cardiovascular events (nonfatal heart attack, nonfatal stroke, and cardiovascular death), but is associated with a significant reduction in the risk of one of these events, nonfatal stroke, although the findings may be limited by the lack of a large study population, according to an article in...

2009-03-24 15:01:11

A chemical component of licorice may offer a new way to prevent colorectal cancer without the adverse side effects of other therapies, U.S. researchers said. The study, published in the Journal of Clinical Investigation, shows that inhibiting the enzyme 11beta-hydroxysteroid dehydrogenase type 2 -- either by treatment with a natural compound found in licorice or by silencing the 11beta-hydroxysteroid dehydrogenase type 2 gene, prevents colorectal cancer progression in mice predisposed to the...

2009-03-18 13:55:00

MORRISTOWN, N.J., March 18 /PRNewswire/ -- Concerns still persist within the general clinical community regarding the cardiovascular and gastrointestinal risk that is associated with the use of analgesics such as the nonsteroidal anti-inflammatory drugs (NSAIDs). In particular, the use of COX-2 selective inhibitor NSAIDs continues to raise the concern of cardio-renal complications not only in the decision making process of physicians but also in the perception of many patients who still...

2009-03-11 11:36:57

A Massachusetts hospital says it has suspended a prominent anesthesiologist who recently announced he had faked multiple research studies on pain medication. The Wall Street Journal said Wednesday that Dr. Scott Reuben was on indefinite leave from his post as head of the acute pain unit at Baystate Medical Center in Springfield, Mass., and was also no longer on the faculty at Tufts University. Reuben's admission that he faked data in 21 studies on painkillers, including Vioxx, has stunned the...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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