Latest Rome process Stories
U-M experts helped develop new evidence-based recommendations put out today by the American College of Gastroenterology U-M Health Minute: Today's top health issues and medical research ANN ARBOR, Mich., Dec. 18 /PRNewswire-USNewswire/ -- Although irritable bowel syndrome (IBS) is the most common disease diagnosed by gastroenterologists, it's also one of the most misunderstood. That's why updated guidelines addressing the management of the condition are being released by the American...
SAN DIEGO, Oct. 7 /PRNewswire/ -- Prometheus Laboratories Inc., a specialty pharmaceutical company, today announced findings from its development of PROMETHEUS(R) IBS Diagnostic, the first and only blood test for irritable bowel syndrome (IBS). The findings suggest measurable differences in the expression of particular biomarkers in blood samples between IBS and non-IBS patients. The identification of these biomarkers, combined with a proprietary algorithm, led to the development of...
ORLANDO, Fla., Oct. 6 /PRNewswire/ -- Ironwood Pharmaceuticals (formerly Microbia) today announced presentation of data from a pair of preclinical studies delineating the role that cyclic guanosine monophosphate (cGMP) plays in alleviating intestinal pain. These studies demonstrate that cGMP inhibits intestinal pain in a preclinical model of intestinal hyperalgesia and desensitizes colonic afferent nerves in a similar model of experimental colitis. These results are from separate, ongoing...
CAMBRIDGE, Mass., Oct. 1 /PRNewswire/ -- Ironwood Pharmaceuticals, Inc. today announced it has raised $50 million in a private equity financing. This capital will be utilized to support the ongoing Phase 3 development program evaluating linaclotide for the treatment of irritable bowel syndrome with constipation (IBS-C) and chronic constipation (CC), to invest in a growing pipeline of internally discovered drug candidates, and to expand commercial capabilities. The financing was led by Morgan...
By PETER GOTT Dear Dr. Gott: I have suffered from Irritable Bowel Syndrome (diarrhea) for 50 years. It began in my early teens. I have tried everything from the early treatment of eating bland foods to today's adding bulk to my diet through the use of roughage and fiber. I still haven't found relief. Everything I do revolves around IBS, from school in my teens, to jobs, family activities and even everyday routines. I am now in my 60s, and retirement is hopefully not far away. I don't want...
SAN DIEGO, May 18 /PRNewswire/ -- New study results indicated that treatment with AMITIZA(R) (lubiprostone) 8 mcg lead to significant relief of overall symptoms of Irritable Bowel Syndrome with Constipation (IBS-C). These results were presented at Digestive Disease Week (DDW) 2008, the largest annual international meeting of digestive disease specialists. "IBS-C is a multi-symptom disorder and is one of the most common conditions seen by gastroenterologists," said William D. Chey, M.D.,...
By Megan Rauscher NEW YORK (Reuters Health) - Treatment with so-called SSRI antidepressants seems to reduce abdominal symptoms and promote overall well being in people with irritable bowel syndrome (IBS), according to results of a small trial. These antidepressants, Dr. Jan Tack told Reuters Health, "could be considered in IBS patients who do not respond well enough to a classical treatment approach." SSRIs are often used in the treatment of IBS "although evidence of their efficacy is...
American College of Gastroenterology 70th Annual Scientific Meeting HONOLULU, October 31, 2005 -- A new study shows that treating Irritable Bowel Syndrome (IBS) with constipation may have a significant impact on absenteeism from work, as well as improving presenteeism "“ defined as coming to work but being less productive. Canadian researchers from The University of Alberta and Novartis Pharmaceuticals Canada presented findings of a study of tegaserod in patients with IBS characterized by...
NEW YORK (Reuters Health) - Childhood abdominal pain is a common complaint, and it may progress to adult irritable bowel syndrome (IBS) in some cases, according to a study in the American Journal of Gastroenterology. IBS is marked by bloating, pain, constipation and diarrhea, and often doesn't seem to have a direct physical cause -- although the symptoms are certainly real. "The natural history of childhood abdominal pain and its association with adult IBS remain poorly described," Dr....
