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Latest Rosiglitazone Stories

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2008-07-02 00:05:00

Speaking before a U.S. advisory panel, Cleveland Clinic cardiologist Steven Nissen said higher standards of testing should be enforced to ensure that new proposed diabetes medicines do not damage patients' hearts. "We have to rule out some level of harm prior to approval," Cleveland Clinic cardiologist Steven Nissen told the panel of experts that advises the Food and Drug Administration. Some experts claim that stricter regulation may require longer clinical testing periods, which could slow...

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2008-01-31 10:20:00

Iowa Senator Charles Grassley said yesterday that Dr. Steven M. Haffner, a well-known diabetes expert at the University of Health Science Center in San Antonio, had leaked confidential, unpublished information to GlaxoSmithKline (GSK) that questioned the safety of the company's diabetes drug Avandia.A New York Times report said that Dr. Haffner had faxed the document, a medical journal article he had agreed to read as part of the normal prepublication peer review process for The New England...

2007-08-02 06:16:49

By Barnett, Anthony Allsworth, Josie; Jameson, Kevin; Mann, Rachel Key words: DPP-4 inhibitor - Glitazone - Incretin - Metformin - Type 2 diabetes - Weight gain ABSTRACT Background: Current American Diabetes Association (ADA)/European Association for the Study of Diabetes (EASD) treatment guidelines recommend metformin (which does not promote weight gain) as the first-line antihyperglycaemic drug for patients with type 2 diabetes. However, when metformin fails, the recommended add-on...

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2007-05-23 14:30:00

How does a drug go from blockbuster to bust? How can big safety issues go undetected in medicines taken by millions of people for many years, as happened this week with the diabetes pill Avandia and a few years ago with the painkiller Vioxx? Or with devices like drug-coated stents, which came under a cloud last year after 6 million heart patients had already received them? All roads - and fingers this week - point to the U.S. Food and Drug Administration. From a company's labs to a consumer's...

2006-09-03 04:09:17

BARCELONA (Reuters) - Patients with type 2 diabetes who have already suffered a first stroke have 47 percent less risk of having a second one if they take Takeda Pharmaceutical Co. Ltd's drug Actos, researchers said on Sunday. The finding, presented at the World Congress of Cardiology, is the latest sign that the oral anti-diabetic medicine provides benefits beyond lowering blood sugar levels. Dr Robert Wilcox of University Hospital, Nottingham, England, said adding Actos to standard...

2006-07-17 13:36:05

By Maggie Fox, Health and Science Correspondent WASHINGTON (Reuters) - Diabetes and pre-diabetic conditions appear to worsen the risk of Alzheimer's disease but drugs that help regulate blood sugar may help patients with dementia as well, researchers report. Several studies presented at a meeting in Madrid, Spain, this week show that patients who take some of the drugs commonly prescribed to type-2 diabetes were less likely to have Alzheimer's disease. The findings worried...

2006-07-17 12:53:50

By Maggie Fox, Health and Science Correspondent WASHINGTON (Reuters) - Diabetes and pre-diabetic conditions appear to worsen the risk of Alzheimer's disease but drugs that help regulate blood sugar may help patients with dementia as well, researchers report. Several studies presented at a meeting in Madrid, Spain, this week show that patients who take some of the drugs commonly prescribed to type-2 diabetes were less likely to have Alzheimer's disease. The findings worried...

2006-07-17 12:45:00

By Maggie Fox, Health and Science Correspondent WASHINGTON (Reuters) - Diabetes and pre-diabetic conditions appear to worsen the risk of Alzheimer's disease but drugs that help regulate blood sugar may help patients with dementia as well, researchers report. Several studies presented at a meeting in Madrid, Spain, this week show that patients who take some of the drugs commonly prescribed to type-2 diabetes were less likely to have Alzheimer's disease. The findings worried Alzheimer's...

2006-02-15 15:13:56

By Will Boggs, MD NEW YORK (Reuters Health) - Better metabolic control of type 2 diabetes can lead to improved "working memory" -- the type of memory people use to keep information in their minds for short-periods of time and to complete day-to-day activities. "Many of the patients with type 2 diabetes may have evidence of mild cognitive dysfunction," Dr. Christopher M. Ryan, from University of Pittsburgh School of Medicine, told Reuters Health. "Improving metabolic control and...

2005-12-15 12:11:59

LONDON (Agence de Presse Medicale) - The European Medicines Agency's scientific committee will investigate a possible link between glitazone therapies and macular oedema, the agency announced on Thursday. The CHMP investigation comes after the EMEA received reports of cases of macular oedema in patients taking GlaxoSmithKline's Avandia/Avandamet (rosiglitazone) and Takeda and Lilly's Actos (pioglitazone). A spokeswoman for the EMEA told APM that since 2000 the agency had been...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.