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Potential Link Between Fungus And Parkinson’s Disease Discovered
2013-11-12 07:11:49

redOrbit Staff & Wire Reports - Your Universe Online An organic compound that is often emitted by fungi has been found to cause symptoms of Parkinson’s disease in fruit flies, and could be linked to the neurodegenerative condition in humans, researchers claim in the Monday’s edition of the journal Proceedings of the National Academy of Sciences (PNAS). Arati Inamdar and Joan Bennett of Rutgers University and their colleagues report that they had discovered a link between the...

2011-03-07 21:25:14

Patients with Parkinson's disease (PD) suffer a specific loss of dopaminergic neurons from the midbrain region that controls motor function. The exact mechanism of this selective neurodegeneration is unclear, though many lines of evidence point to dysfunctional mitochondrial complex I as one root cause of the disease. Yet new research now suggests that defective regulation of microtubules may be responsible for at least some cases of PD. The study appears in the March 7 issue of The Journal...

2011-02-14 16:27:34

For the last several years, neurologists have been probing a connection between Parkinson's disease and problems with mitochondria, the miniature power plants of the cell. Toxins that mimic Parkinson's effects act specifically to poison mitochondria, and mitochondria appear to be damaged in the brain cells that are endangered in the disease. But one unresolved question has been: are mitochondria simply the vulnerable "canaries in the coal mine" or is their deterioration a key step on the way...

2011-02-14 15:33:22

New research shows a link between use of two pesticides, rotenone and paraquat, and Parkinson's disease. People who used either pesticide developed Parkinson's disease approximately 2.5 times more often than non-users. The study was a collaborative effort conducted by researchers at the National Institute of Environmental Health Sciences (NIEHS), which is part of the National Institutes of Health, and the Parkinson's Institute and Clinical Center in Sunnyvale, Calif. "Rotenone directly...

2009-06-04 12:02:45

 The cause of Parkinson's disease (PD), the second most frequent neurodegenerative disease after Alzheimer's disease, is unknown, but in most cases it is believed to involve a combination of environmental risk factors and genetic susceptibility. Laboratory studies in rats have shown that injecting the insecticide rotenone leads to an animal model of PD and several epidemiological studies have shown an association between pesticides and PD, but most have not identified specific pesticides...

2008-06-03 06:00:24

By Robertson, D Ross Smith-Vaniz, William F Coral reefs, one of the most biologically diverse and important ecosystems on Earth, are experiencing unprecedented and increasing ecological decline, yet the fish faunas of such reefs and other tropical shoreline habitats remain poorly known in many areas. Rotenone, a natural substance traditionally used by subsistence fishers, is a uniquely efficient tool for sampling reef and other shore fishes for marine research. Unfortunately, such sampling...

2005-08-24 16:34:23

BUFFALO, N.Y. -- Neuroscientists from the University at Buffalo have described for the first time how rotenone, an environmental toxin linked specifically to Parkinson's disease, selectively destroys the neurons that produce dopamine, the neurotransmitter critical to body movement and muscle control. Microtubules, intracellular highways that transport dopamine to the brain area that controls body movement, are the crucial target, they report. Damage to microtubules prevents dopamine from...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.