Latest RTS,S Stories
New research, by a team from Rhode Island Hospital (RIH), has uncovered a protein, or antigen, that is essential for malaria-causing parasites to escape from red blood cells. This protein also generates antibodies that can hinder the ability of malaria parasites to multiply, which may protect against severe malaria infection.
Researchers say a prominent malaria vaccine could be drastically improved by utilizing the right mix of proteins taken from the surface of the virus.
The world should aim to have vaccines which reduce malaria cases by 75 percent, and are capable of eliminating malaria, licensed by 2030, according to the updated 2013 Malaria Vaccine Technology Roadmap, launched today.
GlaxoSmithKline is expected to seek regulatory approval for a malaria vaccine that recently delivered promising results in a large-scale trial conducted across Africa.
Long-term follow-up of a phase II study from KEMRI-Wellcome Trust Research Programme and Oxford University researchers in Kenya shows that the efficacy of a malaria vaccine candidate, RTS,S, wanes over time and varies with exposure to the malaria parasite.