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Latest S1PR1 Stories

2010-04-20 08:21:31

Anaphylaxis is a severe allergic reaction that is life threatening because it affects the function of multiple organ systems, including the lungs and blood vessels. Its effects on the latter cause them to widen, leading to a dramatic drop in blood pressure, a condition known as anaphylactic shock. New research in mice, performed by Ana Olivera, Juan Rivera, and colleagues, at the National Institutes of Health, Bethesda, has identified a potential new drug target to counteract the widening of...

2010-04-19 09:53:07

Esophageal cancer is one of the most common malignancies worldwide. Its mortality is very high due to relatively late diagnosis and inefficient treatment. The ability to reverse the outcome of esophageal cancer is limited due to a poor understanding of its biology. Progression of esophageal cancer may be associated with sphingosine 1-phosphate (S1P) and its receptors S1P1-5, which play an important role in other cancers. A possible role for S1P and its receptors in human esophageal cells has...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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