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Latest Salk Institute for Biological Studies Stories

2010-11-29 04:00:00

LA JOLLA, Calif., Nov. 29, 2010 /PRNewswire-USNewswire/ -- The Salk Institute for Biological Studies today announced the establishment of the Renato Dulbecco Chair in Genomics and the Roger Guillemin Chair in Neuroscience based on an endowment of $6 million from Irwin Jacobs, chairman of the Salk's Board of Trustees, and his wife Joan Klein Jacobs. "The creation of each chair will pay permanent tribute to the extraordinary research contributions of these two remarkable scientists," said...

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2010-11-04 12:49:37

A study by researchers at the Salk Institute for Biological Studies revealed that stem cells can sense a decrease in available nutrients and respond by retaining only a small pool of active stem cells for tissue maintenance. When, or if, favorable conditions return, stem cell numbers multiply to accommodate increased demands on the tissue. Elucidating the mechanisms by which hormonal signaling influences stem cell behavior under normal conditions and in response to stress provides important...

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2010-10-07 09:55:50

Salk researchers map functional connections between retinal neurons at single-cell resolution By comparing a clearly defined visual input with the electrical output of the retina, researchers at the Salk Institute for Biological Studies were able to trace for the first time the neuronal circuitry that connects individual photoreceptors with retinal ganglion cells, the neurons that carry visuals signals from the eye to the brain. Their measurements, published in the Oct. 7, 2010, issue of the...

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2010-10-04 08:32:12

Like cats, human cells have a finite number of lives-once they divide a certain number of times (thankfully, more than nine) they change shape, slow their pace, and eventually stop dividing, a phenomenon called "cellular senescence". Biologists know that a cellular clock composed of structures at the chromosome end known as telomeres records how many "lives" a cell has expended. Up to now, investigators have not yet defined how the clock's ticking signals the approach of cellular oblivion. In...

2010-09-23 13:00:00

SAN DIEGO, Sept. 23 /PRNewswire/ -- The Salk Institute of Biological Sciences has selected San Diego solar company Stellar Solar to design and install a new 500 kW rooftop solar electric system for its architecturally renowned campus in La Jolla, according to Tim Ball, the Institute's senior director of facilities services. The project also combines the sustainability of solar energy with the sensibility of architectural preservation, Ball pointed out. The buildings were completed in 1965...

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2010-08-25 14:27:11

Study suggests potential for new oncolytic therapies A novel mechanism used by adenovirus to sidestep the cell's suicide program, could go a long way to explain how tumor suppressor genes are silenced in tumor cells and pave the way for a new type of targeted cancer therapy, report researchers at the Salk Institute for Biological Studies in the Aug. 26, 2010 issue of Nature. When a cell is under stress, the tumor suppressor p53 springs into action activating an army of foot soldiers that...

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2010-08-16 08:42:46

Brainwave activity associated with language processing differs sharply in 2 disorders with opposite social profiles: Autism and Williams syndrome People with Williams syndrome-known for their indiscriminate friendliness and ease with strangers-process spoken language differently from people with autism spectrum disorders-characterized by social withdrawal and isolation-found researchers at the Salk Institute for Biological Studies. Their findings, to be published in a forthcoming issue of...

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2010-07-02 08:11:47

Stem cells in the brain remain dormant until called upon to divide and make more neurons. However, little has been known about the molecular guards that keep them quiet. Now scientists from the Salk Institute for Biological Studies have identified the signal that prevents stem cells from proliferating, protecting the brain against too much cell division and ensuring a pool of neural stem cells that lasts a lifetime. The research, which was published in the July 1 issue of Cell Stem Cell,...

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2010-06-25 08:11:42

For a plant, light is life. It drives everything from photosynthesis to growth and reproduction. Yet the chain of molecular events that enables light signals to control gene activity and ultimately a plant's architecture had remained in the dark. Now a team of researchers from the Salk Institute for Biological Studies and Duke University have identified the courier that gives the signal to revamp the plant's gene expression pattern after photoreceptors have been activated by light. "Light is...

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2010-06-11 07:03:10

Nuclear pores are the primary gatekeepers mediating communication between a cell's nucleus and its cytoplasm. Recently these large multiprotein transport channels have also been shown to play an essential role in developmental gene regulation. Despite the critical role in nuclear function, however, nuclear pore complexes remain somewhat shadowy figures, with many details about their formation shrouded in mystery. Now a team of investigators from the Salk Institute for Biological Studies has...


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blee
  • Color; hue; complexion.
This word is Middle English in origin.
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