Latest Sarcoma Stories

By Woodall, Charles E Scoggins, Charles R; Lewis, Angela M; McMasters, Kelly M; Martin, Robert C G Malignant epithelioid hemangioendothelioma is a rare hepatic tumor of vascular origin. It is most commonly found in young to middle aged women, and the tumors vary in reported malignant potential. Compounds such as oral contraceptive pills, poly vinyl chloride, and Thorotrast have been identified as risk factors for subsequent disease development. Radiologic ("lollipop" sign, capsular...

By Frattini, Jared C Sosa, Julie Ann; Carmack, Susanne; Robert, Marie E * Data from the nuclear reactor explosion in Chernobyl and the atomic bomb detonations in Hiroshima and Nagasaki demonstrated an association between ionizing radiation and tumoriogenesis. There is a significant association between external beam radiation and radiation-induced sarcoma. Sclerosing epithelioid fibrosarcoma is a rare form of malignant fibrosarcoma that is low grade and indolent with distinct...

By Grabowski, Julia Salzstein, Sidney L; Sadler, Georgia R; Blair, Sarah L Malignant phyllodes tumor (MPT) is a rare breast malignancy. Because of the scarcity of the disease, there are no evidence-based treatment or follow-up guidelines established. This study evaluated the survival of MPT patients to create recommendations for management. We identified 752 cases of malignant phyllodes tumors in the California Cancer Registry from the years 1988 to 2003. Relative survival was determined...

By JESSICA FARGEN At one of the country's most esteemed cancer centers, where great phycisians combat the rarest diseases, Dr. Monica Bertagnolli takes the cases no one else can. Colleagues say her surgical skills save patients who have few places to turn to rid their bodies of stubborn and deadly cancers. And her prowess in the lab has influenced the drugs that tens of thousands take to prevent colon cancer. "I would consider her one of our superstars," said Dr. Michael Zinner, chief of...

NEW YORK (Reuters Health) - Although as many as 70 percent of patients who have the localized stage of the bone cancer osteosarcoma survive after surgery and chemotherapy, the overall survival rate after recurrence is less than 30 percent, researchers report.However, lead investigator Dr. Paul A. Meyers told Reuters Health, "the chances of survival are better for patients whose recurrence is detected after a longer interval from the completion of initial therapy and for patients whose...

Paris, France, Thursday 3 November 2005 - Updated results from a Phase III trial presented at the 13th European Cancer Conference (ECCO) show that sunitinib (SU11248) prolongs both progression-free and overall survival in patients with progressive metastatic and/or unresectable GIST whose disease has failed to respond to the standard therapy - imatinib mesylate. This study was a double-blind, placebo-controlled, international, multicentre, Phase III trial involving 312 patients with GIST...

TUESDAY, Nov. 30 (HealthDayNews) -- The drug Gleevec (imatinib) has shown promising activity in AIDS-related Kaposi's sarcoma, says a small study in the Nov. 30 issue of the Journal of Clinical Oncology. The drug inhibits pathways that spur cancer growth, which led to regression of tumors in five patients within four weeks, the study said. With the other five patients, the disease stabilized and they didn't develop any new tumors. "Imatinib is a targeted therapy originally shown to be...