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Implications for treating muscular dystrophy and other muscle wasting diseases
The study of muscular system protein myostatin has been of great interest to researchers as a potential therapeutic target for people with muscular disorders.
When a muscle is damaged, dormant adult stem cells called satellite cells are signaled to “wake up” and contribute to repairing the muscle.
Researchers have long questioned why patients with Duchenne muscular dystrophy (DMD) tend to manage well through childhood and adolescence, yet succumb to their disease in early adulthood, or why elderly people who lose muscle strength following bed rest find it difficult or impossible to regain.
Information about how the cells move could help patients with muscular dystrophy, MU scientist says.