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2014-04-04 10:29:01

When cannibals ate brains of people who died from prion disease, many of them fell ill with the fatal neurodegenerative disease as well. Likewise, when cows were fed protein contaminated with bovine prions, many of them developed mad cow disease. On the other hand, transmission of prions between species, for example from cows, sheep, or deer to humans, is—fortunately—inefficient, and only a small proportion of exposed recipients become sick within their lifetimes. A study published on...

2012-11-30 16:13:59

Prion diseases represent a family of neurodegenerative disorders associated with the loss of brain cells and caused by proteins called prions (derived from 'protein' and 'infection'). The diseases are found in both humans and animals, such as Creutzfeld-Jakob disease and mad cow disease respectively. Although mostly harmless, prions can transform into infectious agents, which accumulate in the brain and destroy the nervous tissue. But how exactly does the accumulation of prions cause...

Mad Cow Detection Hope
2012-09-13 08:30:04

April Flowers for redOrbit.com - Your Universe Online Medical researchers from the University of Melbourne believe that a simple blood test for Creutzfeldt-Jakob Disease and Bovine Spongiform Encephalopathy, aka Mad Cow disease, is a step closer following a recent breakthrough. Using newly available genetic sequencing, researchers have discovered cells infected with prions (the infectious protein responsible for these diseases) release particles which contain easily recognized signature...

2011-05-18 16:48:55

Certain lichens can break down the infectious proteins responsible for chronic wasting disease (CWD), a troubling neurological disease fatal to wild deer and elk and spreading throughout the United States and Canada, according to U.S. Geological Survey research published today in the journal PLoS ONE. Like other "prion" diseases, CWD is caused by unusual, infectious proteins called prions. One of the best-known of these diseases is "mad cow" disease, a cattle disease that has infected humans....

2011-05-10 15:02:55

Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), report that they have developed a method"”10,000 times more sensitive than other methods"”to detect variant Creutzfeldt-Jacob disease (vCJD) in blood plasma. vCJD is a type of prion disease in humans that leads to brain damage and death. The NIAID researchers also used the test to rapidly detect scrapie, a prion disease of sheep, in infected hamsters,...

2011-02-17 21:07:19

Researchers at the University of California, San Diego School of Medicine have identified the motors that move non-infectious prion proteins (PrPC) "“ found within many mammalian cells "“ up and down long, neuronal transport pathways. Identifying normal movement mechanisms of PrPC may help researchers understand the spread of infectious prions within and between neurons to reach the brain, and aid in development of therapies to halt the transport. Their study is published in the...

2010-12-17 16:15:21

Findings Point to Normal Prion Protein as Most Effective Therapeutic Target for "Mad Cow" and Related Diseases Scientists from the Florida campus of The Scripps Research Institute have shown that prions, bits of infectious protein that can cause fatal neurodegenerative disease such as bovine spongiform encephalopathy (BSE) or "mad cow disease," have the ability to adapt to survive in a new host environment. In this regard, although they lack DNA and RNA, they behave much like viruses,...

2010-12-03 13:27:50

A fast test to diagnose fatal brain conditions such as mad cow disease in cattle and Creutzfeldt-Jakob disease in humans could be on the horizon, according to a new study from National Institutes of Health scientists. Researchers at NIH's National Institute of Allergy and Infectious Diseases (NIAID) have developed a highly sensitive and rapid new method to detect and measure infectious agents called prions that cause these diseases. "Although relatively rare in humans and other animals, prion...

2010-12-01 21:11:38

New research in the FASEB Journal suggests that plasminogen, which helps break down blood clots, puts rogue prion proteins into overdrive, causing devastating brain diseases The joy of a juicy hamburger could make a comeback thanks a new discovery by scientists from the University of Kentucky. In a new research report in the December 2010 print issue of The FASEB Journal (http://www.fasebj.org), scientists found that a protein our body uses to break up blood clots speeds up the progress of...

2010-10-19 20:39:16

The eyes of sheep infected with scrapie "“ a neurological disorder similar to mad cow disease "“ return an intense, almost-white glow when they're hit with blue excitation light, according to a research project led by Iowa State University's Jacob Petrich. The findings suggest technologies and techniques can be developed to quickly and noninvasively test for transmissible spongiform encephalopathies, progressive and fatal neurological diseases such as mad cow disease in cattle and...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.