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Latest Scripps Research Institute Stories

2014-07-17 16:25:53

Publication in Science Unveils Novel, Diverse and Separate Biological Functions That Can Be Harnessed Therapeutically to Mediate a Wide Range of Human Disease SAN DIEGO and HONG KONG, July 17, 2014 /PRNewswire/ -- aTyr Pharma, an innovative rare disease therapeutics enterprise, and its subsidiary in Hong Kong, Pangu Biopharma (aTyr), announced the discovery of a new class of human proteins with therapeutic relevance for a wide range of diseases. The findings unveiled today in a...

2014-07-09 11:30:11

The Scripps Research Institute Scientists from the Florida campus of The Scripps Research Institute (TSRI) have discovered a surprising new role for a pair of compounds—which have the potential to alter circadian rhythm, the complex physiological process that responds to a 24-hour cycle of light and dark and is present in most living things. At least one of these compounds could be developed as a chemical probe to uncover new therapeutic approaches to a range of disorders, including...

2014-06-24 12:27:33

PHILADELPHIA, June 24, 2014 /PRNewswire-USNewswire/ -- Twenty-two outstanding early-career researchers were named Pew Scholars in the Biomedical Sciences today by The Pew Charitable Trusts. The scholars--whose fields of study range from genetics to neuroscience to biophysics--will receive flexible funding to investigate some of the world's most pressing health problems. They join a community of more than 500 Pew scholars whose ranks include multiple recipients of Nobel Prizes, Lasker...

2014-05-23 12:24:55

LA JOLLA, Calif., May 23, 2014 /PRNewswire-USNewswire/ -- The California Institute for Biomedical Research (Calibr) has received a Translation Award from the Wellcome Trust to develop a novel semi-synthetic antibody-based immunotherapy to treat hormone-refractory prostate cancer. The novel therapeutic agent engages the patient's own immune system to selectively destroy prostate tumor cells. This approach offers a potentially more efficacious and safer alternative to traditional...

2014-05-20 12:20:42

Scripps Research Institute Chemists at The Scripps Research Institute (TSRI) have determined the correct structure of a highly promising anticancer compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials in cancer patients. The new report, published this week by the international chemistry journal Angewandte Chemie, focuses on a compound called TIC10. In the new study, the TSRI scientists show that TIC10's structure differs subtly from a version published...

2014-05-19 08:29:14

PASADENA, Calif., May 19, 2014 /PRNewswire/ -- Meditope Biosciences, Inc., a biotechnology company developing novel antibody-drug conjugates (ADC) using its proprietary monoclonal antibody (mAb) technology platform, today announced the appointment of C. Dan Dumitru, M.D., Ph.D., as Vice President of Translational Research. "We are delighted to expand our highly focused team to include Dan, who brings a strong background in preclinical and translational drug development for biologics...

2014-05-16 08:25:39

LA JOLLA, Calif., May 16, 2014 /PRNewswire-USNewswire/ -- Mice crippled by an autoimmune disease similar to multiple sclerosis (MS) regained the ability to walk and run after a team of researchers led by scientists at The Scripps Research Institute (TSRI), University of Utah and University of California (UC), Irvine implanted human stem cells into their injured spinal cords. Remarkably, the mice recovered even after their bodies rejected the human stem cells. "When we implanted the...

2014-05-12 12:31:20

LA JOLLA, Calif., May 12, 2014 /PRNewswire-USNewswire/ -- The California Institute for Biomedical Research (Calibr) has received a grant from the Bill & Melinda Gates Foundation to develop an Integrated Drug Discovery Platform for Diseases of the Developing World (IDDP). The goal will be to identify innovative new therapeutics for the treatment of diseases of the developing world. The program will leverage ongoing research efforts and infrastructure at Calibr, as well as draw upon...

2014-05-07 12:31:05

First example of in vivo replication of a synthetic DNA base pair published in Nature SAN DIEGO, May 7, 2014 /PRNewswire/ -- Synthorx Inc. announced today the official launch of the company, which will be focused on using synthetic biology to improve the discovery and development of new medicines, diagnostics and vaccines. In addition, research was published today in Nature by Floyd Romesberg, Ph.D., Synthorx's co-founder and associate professor of The Scripps Research Institute,...

2014-04-24 12:30:09

NEW YORK, April 24, 2014 /PRNewswire-USNewswire/ -- Scientists from The Scripps Research Institute (TSRI) and the International AIDS Vaccine Initiative (IAVI) have discovered a new vulnerable site on HIV that antibodies can attack to prevent infection from a broad range of the virus' many variants. http://photos.prnewswire.com/prnvar/20131210/DC30761LOGO "HIV has very few known sites of vulnerability, but in this work we've described a new one, and we expect it will be useful in developing a...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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