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Last updated on April 23, 2014 at 13:55 EDT

Latest Scripps Research Institute Stories

2013-08-09 10:15:15

A small group of immune-regulating molecules, when overproduced even moderately, can trigger the blood cancers known as lymphomas, according to a new study led by scientists from The Scripps Research Institute (TSRI). The six “microRNA” molecules were already known to be overproduced in lymphomas and in many other human cancers, but no one had demonstrated that they can be the prime cause of such cancers—until now. The new study also identified the major biological pathways through...

2013-07-31 08:30:47

HUNTSVILLE, Ala., July 31, 2013 /PRNewswire/ -- Serina Therapeutics, Inc., a pharmaceutical research and development company that has developed a proprietary, patented polymer technology for drug development, announced today that the company has entered into a research agreement with the Scripps Research Institute for development of polymer-antibody drug conjugates (Polymer-ADCs). The nature of the agreement and the financial terms were not disclosed. "Antibody drug conjugates...

2013-07-18 08:29:01

Agreement marks first partnership of its kind between a research institution and reagents company; third major deal in TSRI's new partnering strategy SAINT LOUIS and LA JOLLA, Calif., July 18, 2013 /PRNewswire/ -- Sigma-Aldrich Corporation (Nasdaq: SIAL) today announced a partnership with The Scripps Research Institute (TSRI) to fund research and provide immediate, day-of-publication access to TSRI researchers' discoveries for the synthesis and analysis of potential drugs. The...

3D Structure Of Key Drug Target For Diabetes Found
2013-07-18 08:27:10

Scripps Research Institute An international team led by scientists at The Scripps Research Institute (TSRI) has determined and analyzed the three-dimensional atomic structure of the human glucagon receptor. The receptor, found mainly on liver and kidney cells, helps regulate glucose levels in the bloodstream and is the target of potential therapeutic agents for type 2 diabetes. "Our data should change the current view of how drugs are designed with this and related receptors," said TSRI...

2013-07-17 23:04:31

New members from PwC, The Scripps Research Institute, Latham & Watkins and Thermo Fisher Scientific strengthen current board La Jolla, Calif. (PRWEB) July 17, 2013 California Healthcare Institute (CHI) announced today the election of four senior executives to serve on its board of directors: Peter Claude, partner at PwC US; Dr. Michael Marletta, president and CEO of The Scripps Research Institute (TSRI); Alan Mendelson, partner at Latham & Watkins; and Dr. Marc Tremblay,...

2013-07-15 13:33:43

An international group of scientists has shown that a drug candidate designed by scientists from the Florida campus of The Scripps Research Institute (TSRI) significantly increases exercise endurance in animal models. These findings could lead to new approaches to helping people with conditions that acutely limit exercise tolerance, such as obesity, chronic obstructive pulmonary disease (COPD) and congestive heart failure, as well as the decline of muscle capacity associated with aging....

2013-07-11 12:27:44

LA JOLLA, Calif., July 11, 2013 /PRNewswire-USNewswire/ -- Scientists at The Scripps Research Institute (TSRI) have published one of the first laboratory studies of MDPV, an emerging recreational drug that has been sold as "bath salts." The TSRI researchers confirmed the drug's powerful stimulant effects in rats and found evidence that it could be more addictive than methamphetamine, one of the most addictive substances to date. "We observed that rats will press a lever more often to...

2013-07-01 08:27:02

- ChromaDex's Niagen(TM) is the First and Only Commercially Available Nicotinamide Riboside - IRVINE, Calif., July 1, 2013 /PRNewswire/ -- ChromaDex Corp.(®) (OTCBB: CDXC), an innovative natural products company that provides proprietary, science-based solutions and ingredients to the dietary supplement, food & beverage, animal health, cosmetic and pharmaceutical industries, announced today it has entered into a material transfer agreement (MTA) with The Scripps Research...

2013-06-13 09:58:47

Scientists at The Scripps Research Institute (TSRI) have found evidence that an emotion-related brain region called the central amygdala–whose activity promotes feelings of malaise and unhappiness–plays a major role in sustaining cocaine addiction. In experiments with rats, the TSRI researchers found signs that cocaine-induced changes in this brain system contribute to anxiety-like behavior and other unpleasant symptoms of drug withdrawal–symptoms that typically drive an...

2013-06-06 19:58:39

Humans have been raising cows for their meat, hides and milk for millennia. Now it appears that the cow immune system also has something to offer. A new study led by scientists from The Scripps Research Institute (TSRI) focusing on an extraordinary family of cow antibodies points to new ways to make human medicines. “These antibodies´ structure and their mechanism for creating diversity haven´t been seen before in other animals´ antibodies,” said Vaughn V....