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Latest Scripps Research Institute Stories

2013-10-03 16:11:47

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a new drug candidate for an inherited form of cancer with no known cure. The new study showed the drug candidate—known as FRAX97—slowed the proliferation and progression of tumor cells in animal models of Neurofibromatosis type 2. This inherited type of cancer, caused by mutations in the anti-tumor gene NF2, leads to tumors of the auditory nerve that connects the inner ear to the brain. The...

2013-10-03 09:06:40

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have discovered some key features that explain just what turns on a protein that is considered to be a master regulator of how the human body uses and stores energy. The new discoveries could help in the design and development of new therapeutics to treat metabolic disease such as diabetes and obesity—and perhaps some cancers as well. The new study, led by Patrick R. Griffin, chair of the TSRI Department of...

2013-10-01 15:29:50

A team led by scientists at The Scripps Research Institute (TSRI) has created the first comprehensive roadmap of the protein interactions that enable cells in the pancreas to produce, store and secrete the hormone insulin. The finding makes possible a deeper scientific understanding of the insulin secretion process—and how it fails in insulin disorders such as type 2 diabetes. “The development of this insulin interaction map is unprecedented, and we expect it to lead us to new...

2013-09-30 12:48:15

Findings point to new approach to drug design Highlighting an important but unexplored area of evolution, scientists at The Scripps Research Institute (TSRI) have found evidence that, over hundreds of millions of years, an essential protein has evolved chiefly by changing how it moves, rather than by changing its basic molecular structure. The work has implications not only for the understanding of protein evolution, but also for the design of antibiotics and other drugs that target the...

2013-09-27 23:25:06

Scientists may soon develop a pill that removes traumatic memories from your brain. Fort Lauderdale, Florida (PRWEB) September 27, 2013 Mental health treatment centers around the world are reviewing a newly released study from the Scripps Research Institute that may allow scientists and drug manufacturers to eventually create memory blocking prescription drugs. Scientists at Scripps Research Institute have studied rat brains and discovered that they are able to eliminate certain strong,...

2013-09-27 10:48:02

It’s difficult and time-consuming to produce accurate computer models of molecules, primarily because traditional modeling methods are limited in their ability to handle alternative molecular shapes and, consequently, are subject to multiple errors. Moreover, the traditional approach uses mathematical formulas or algorithms that are run sequentially, refining the structural details of the model with each separate algorithm—a method that has been revolutionized by personal computing,...

2013-09-17 11:09:09

Scientists at The Scripps Research Institute (TSRI) have found a way to make dramatic improvements to the cancer cell-killing power of vinblastine, one of the most successful chemotherapy drugs of the past few decades. The team’s modified versions of vinblastine showed 10 to 200 times greater potency than the clinical drug. Even more significantly, these new compounds overcome the drug resistance that emerges upon treatment relapse, which renders continued or subsequent vinblastine...


Word of the Day
lambent
  • Licking.
  • Hence Running along or over a surface, as if in the act of licking; flowing over or along; lapping or bathing; softly bright; gleaming.
This word comes the Latin 'lambere,' to lick.
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