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Latest Sean Morrison Stories

Door To Undiscovered World Of Biology Opened By Stem Cell Study
2014-03-10 08:19:39

UT Southwestern Medical Center For the first time, researchers have shown that an essential biological process known as protein synthesis can be studied in adult stem cells – something scientists have long struggled to accomplish. The groundbreaking findings from the Children's Medical Center Research Institute at UT Southwestern (CRI) also demonstrate that the precise amount of protein produced by blood-forming stem cells is crucial to their function. The discovery, published online...

2012-01-26 02:12:48

Scientists with the new Children´s Research Institute at UT Southwestern Medical Center have identified the environment in which blood-forming stem cells survive and thrive within the body, an important step toward increasing the safety and effectiveness of bone-marrow transplantation. Institute investigators led by Dr. Sean Morrison asked which cells are responsible for the microenvironment that nurtures haematopoietic stem cells, which produce billions of new blood cells every day....

2010-12-01 22:49:16

University of Michigan researchers have discovered that a protein known to regulate cellular metabolism is also necessary for normal cell division in blood-forming stem cells. Loss of the protein results in an abnormal number of chromosomes and a high rate of cell death. The finding demonstrates that stem cells are metabolically different from other blood-forming cells, which can divide without the protein, Lkb1. This metabolic difference could someday be used to better control the behavior...

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2009-12-17 06:50:00

The most widely used human embryonic stem cell lines lack genetic diversity, a finding that raises social justice questions that must be addressed to ensure that all sectors of society benefit from stem cell advances, according to a University of Michigan research team. In the first published study of its kind, the U-M team analyzed 47 embryonic stem cell lines, including most of the lines commonly used by stem cell researchers. The scientists determined the genetic ancestry of each line and...

2009-12-16 16:01:00

ANN ARBOR, Mich., Dec. 16 /PRNewswire-USNewswire/ --The most widely used human embryonic stem cell lines lack genetic diversity, a finding that raises social justice questions that must be addressed to ensure that all sectors of society benefit from stem cell advances, according to a University of Michigan research team. In the first published study of its kind, the U-M team analyzed 47 embryonic stem cell lines, including most of the lines commonly used by stem cell researchers. The...

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2008-12-04 15:00:00

Researchers have reported that a single cancer cell has enough power to develop a separate cancerous tumor.Dr Sean Morrison led a team of researchers from the Howard Hughes Medical Institute and the University of Michigan reported their findings in the journal Nature. Researchers injected melanoma cells into mice with weakened immune systems. They discovered that 250,000 times as many mice developed tumors. When single melanoma cells were used, they discovered that roughly one in four of them...

2005-06-30 13:37:28

ANN ARBOR, Mich. "“ Scientists at the University of Michigan Medical School have discovered the biological equivalent of a grocery store bar code on the surface of primitive, blood-forming stem cells in mice. Called hematopoietic stem cells, they give rise to all the different types of specialized cells found in blood. By reading the bar code, scientists can separate stem cells from their more advanced descendants "“ progenitor cells that already are committed to becoming one...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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