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Latest Secondary structure Stories

2012-01-10 23:21:53

New method for nucleic acid analysis In the world of biomolecules such as proteins and the hereditary nucleic acids DNA and RNA, three-dimensional structure determines function. Analysis of the passage of such molecules through nanopores offers a relatively new, but highly promising, technique for obtaining information about their spatial conformations. However, interactions between the test molecules and the proteins used as pores have so far hindered quantitative analysis of the behavior...

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2010-12-15 11:07:28

Interactions between proteins are at the heart of cellular processes, and those interactions depend on the interfaces where the direct physical contact occurs. A new study published this week suggests that there may be roughly a thousand structurally-distinct protein-protein interfaces "“ and that their structures depend largely on the simple physics of the proteins. Believed to be the first systematic study of the nature of the protein-protein interfaces, the research could help...

2010-01-07 18:44:20

University of Michigan researchers have discovered the rules that dictate the three-dimensional shapes of RNA molecules, rules that are based not on complex chemical interactions but simply on geometry. The work, done by a team led by Hashim M. Al-Hashimi, is described in the Jan. 8, 2010, issue of the journal Science. "RNA is a very floppy molecule that often functions by binding to something else and then radically changing shape," said Al-Hashimi, who is the Robert L. Kuczkowski Professor...