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Latest Secreted frizzled-related protein 1 Stories

2013-10-14 11:21:22

The study's authors identify new genetic pathways and new genes involved in bladder cancer; The genetic signature of these patients is a first step towards understanding the biology of this illness and improving patient management Bladder cancer represents a serious public health problem in many countries, especially in Spain, where 11,200 new cases are recorded every year, one of the highest rates in the world. The majority of these tumors have a good prognosis -- 70-80% five-year...

2012-05-31 01:31:03

Breast-cancer researchers at the University of Wisconsin-Madison have found that two related receptors in a robust signaling pathway must work together as a team to maintain normal activity in mammary stem cells. Mammary stem cells produce various kinds of breast cell types. They may also drive the development and growth of malignant breast tumors. Published recently in the Journal of Biological Chemistry, the research also suggests that a new signaling pathway may be involved, a...

2012-05-22 22:57:04

The impact and influence of thirty years of research into the Wnt/beta-catenin signaling pathway are highlighted in a special issue of The EMBO Journal. “Three decades of Wnt signalling” summarizes many of the crucial scientific developments that have taken place since the discovery of the first mammalian Wnt gene in 1982. The reviews also describe many of the crucial research findings that have established the pathway as one of the fundamental signal transduction mechanisms in...

2012-05-03 19:28:41

Lawson research provides new insight into disease pathology In a new study from Lawson Health Research Institute, Dr. Joseph Torchia has identified a new genetic pathway influencing the spread of cancer cells. The discovery of this mechanism could lead to new avenues for treatment. Regular cell division is regulated by methylation, a series of chemical changes. Methylation modifies DNA to ensure cells divide at a healthy, balanced rate. In cancer, the methylation process is unbalanced,...

2011-09-21 19:09:39

Brain disorder accounts for 1 in 4 cases No cure exists for frontotemporal dementia, which strikes between the ages of 40 and 64 and accounts for at least one in four cases of early-onset dementia. Caused by the death of cells in the front and sides of the brain, the disease can lead to dramatic changes in a patient's personality and behavior, including the loss of the ability to communicate. Now UCLA scientists have discovered that a key signaling pathway plays an important role in the...

2011-09-01 17:08:32

Salk scientists discover a highly conserved mechanism governing brain development If you think today's political rhetoric is overheated, imagine what goes on inside a vertebrate embryo. There, two armies whose agendas are poles apart, engage in a battle with consequences much more dire than whether the economy will recover---- they are battling for whether you (or frogs or chickens) will have a forebrain. In a study published in the August 19 online edition of Genes & Development,...

2011-05-23 21:59:37

Researchers from Mount Sinai School of Medicine have discovered a protein signaling pathway that becomes hyperactivated in human sarcoma cells, suggesting that medications to inhibit this pathway may be effective in the treatment of human sarcomas. The research is published in the current issue of the journal Cancer Cell. A team of researchers led by Stuart Aaronson, MD, Jack and Jane B. Aron Professor and Chairman of the Department of Oncological Sciences at Mount Sinai School of Medicine,...

2011-05-23 07:25:36

(Ivanhoe Newswire) -- Researchers say they have discovered a new drug target for squamous cell carcinoma -- the second most common form of skin cancer. Each year, more than 700,000 new cases of squamous cell carcinoma are diagnosed. This type of skin cancer develops in the cells that make up most of the skin's upper layers. Squamous cell carcinomas are most commonly found in areas exposed to the sun such as the rim of the ear, lower lip, face, scalp, neck, hands, arms and legs. Investigators...

2011-05-19 23:18:24

Researchers find that the protein alpha-catenin acts as a tumor suppressor and they reveal the mechanism by which it controls cell growth Researchers at Fred Hutchinson Cancer Research Center have discovered a new drug target for squamous cell carcinoma "“ the second most common form of skin cancer. Scientists in the laboratory of Valeri Vasioukhin, Ph.D., have found that a protein called alpha-catenin acts as a tumor suppressor and they also have unlocked the mechanism by which this...


Word of the Day
holluschickie
  • A 'bachelor seal'; a young male seal which is prevented from mating by its herd's older males (mated bulls defending their territory).
This comes from the Russian word for 'bachelors.'
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