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Latest Secretion Stories

2014-07-17 16:13:25

Washington University School of Medicine Scientists may be able to entomb the malaria parasite in a prison of its own making, researchers at Washington University School of Medicine in St. Louis report July 16 in Nature. As it invades a red blood cell, the malaria parasite takes part of the host cell's membrane to build a protective compartment. To grow properly, steal nourishment and dump waste, the parasite then starts a series of major renovations that transform the red blood cell...

Work On Microbial Signaling Offers A Window Into Better Biofuels, Human Health
2014-04-25 03:28:23

Tom Rickey, DOE/Pacific Northwest National Laboratory A common plant puts out a welcome mat to bacteria seeking to invade, and scientists have discovered the mat's molecular mix. The study published this week in the Proceedings of the National Academy of Sciences reveals new targets during the battle between microbe and host that researchers can exploit to protect plants. The team showed that the humble and oft-studied plant Arabidopsis puts out a molecular signal that invites an...

2014-02-10 11:17:25

Twenty proteins specifically secreted by primary effusion lymphoma cell lines identified, according to new research published in The American Journal of Pathology Primary effusion lymphoma (PEL) is a rare B-cell neoplasm distinguished by its tendency to spread along the thin serous membranes that line body cavities without infiltrating or destroying nearby tissue. By growing PEL cells in culture and analyzing the secretome (proteins secreted into cell-conditioned media), investigators have...

Intracellular ABC Transporters Allow Leaf Beetle Larvae To Accumulate Defensive Substances When Feeding
2013-12-09 11:58:38

Max Planck Institute for Chemical Ecology Similar membrane proteins play a crucial role in the transport of toxic substances out of the cell Scientists at the Max Planck Institute for Chemical Ecology in Jena, Germany, have discovered the decisive biological stimulator for the accumulation of defensive substances in leaf beetle larvae used by the insects to fend off predators: ABC transport proteins, which are found in large quantities in glandular cells of the larvae. The poplar leaf...

2013-10-24 10:26:37

Similar to passengers on an urban transit system, every protein made in the cell has a specific destination and function. Channels in cell membranes help direct these proteins to their appropriate target. Researchers at Boston University School of Medicine (BUSM) and their colleagues have now captured images of these channels as they open to allow proteins to pass through a membrane, while the proteins are being made. These findings are published as a Letter in Nature (Park, E. et al. 2013)....

Role That Flagellum Plays In Helping E. Coli Colonize Rough Surfaces Revealed
2013-04-11 13:06:15

Harvard University New research from Harvard University helps to explain how waterborne bacteria can colonize rough surfaces–even those that have been designed to resist water. A team of materials scientists and microbiologists studied the gut bacterium Escherichia coli, which has many flagella that stick out in all directions. The researchers found that these tails can act as biological grappling hooks, reaching far into nanoscale crevices and latching the bacteria in place....

2012-12-06 11:19:38

Combining 2 methods provides a real-time view of bedbug chemical signals Bed bugs exchange specific chemical signals corresponding to particular behaviors, and researchers have now combined two unusual technologies to sniff out these signals in a matter of seconds. The results are published December 5 in the open access journal PLOS ONE by Ole Kilpinen and colleagues from Aarhus University, Denmark, and reveal previously unknown aspects of bed bug lifestyles and mating behaviors....

2012-10-19 01:44:17

Chemists at the California Institute of Technology (Caltech) have managed, for the first time, to simulate the biological function of a channel called the Sec translocon, which allows specific proteins to pass through membranes. The feat required bridging timescales from the realm of nanoseconds all the way up to full minutes, exceeding the scope of earlier simulation efforts by more than six orders of magnitude. The result is a detailed molecular understanding of how the translocon works....

2012-05-10 13:55:04

Journal of Biological Chemistry: Mechanism of bacterial transport system published In order to interact with the environment, bacteria secrete a whole arsenal of proteins. Researchers have now found how one of the transportation systems used for this purpose — the type VI secretion system — works for the single-celled organism Agrobacterium tumefaciens. They have identified the relevant transport proteins and their energy suppliers. With colleagues at the Academia Sinica in...


Latest Secretion Reference Libraries

45_d2fcb725ecc7dee8dbe887c765abd299
2011-04-14 14:17:06

Agrobacterium tumefaciens is the causal agent of crown gall disease (the formation of tumours) in over 140 species of dicot. It is rod shaped. Symptoms are caused by the insertion of a small segment of DNA into the plant cell. It is an alphaproteobacterium of the family Rhizobiaceae which includes the nitrogen fixing legume symbionts. They are pathogenic and provide no benefit to the plant. It also affects a wide variety of plants. In an economical sense it affects walnuts, grape vines,...

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Word of the Day
barghest
  • A goblin in English folklore, often appearing in the shape of a large dog and believed to portend imminent death or misfortune.
  • A ghost, wraith, hobgoblin, elf, or spirit.
The origin of 'barghest' is not known, but it may be from perhaps burh-ghest, town-ghost, or German Berg-geist (mountain spirit) or Bär-geist (bear-spirit).
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