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Latest Sentinel lymph node Stories

2011-08-08 06:49:29

(Ivanhoe Newswire) -- A new study shows removing lymph nodes because of the presence of microscopic cancer cells found in the sentinel node has no impact on survival among women with early-stage breast cancer. Researchers studied more than 5,000 women with breast cancer at 126 sites around the country. All the participants underwent breast-conserving surgery and sentinel lymph node dissection. The sentinel lymph node is the one that is closest to the tumor. Results showed survival outcomes...

2011-08-05 14:11:07

Study refutes controversy about technique in delicate head, neck region A common technique for determining whether melanoma has spread can be used safely and effectively even in tumors from the head and neck area, according to a new study from the University of Michigan Comprehensive Cancer Center. Sentinel lymph node biopsy involves injecting a special dye to identify the first node where cancer would likely spread. If that node is clean, patients can avoid further debilitating surgery to...

2011-07-26 22:03:11

Study reported in Journal of the American Medical Association A new study shows that removing lymph nodes due to the presence of occult, or microscopic, cancer cells found in the sentinel lymph node "“ the one closest to the tumor -- has no impact on survival outcomes of women with early-stage breast cancer. The principal investigator of the study is Armando E. Giuliano, MD, of Cedars-Sinai, who already is renowned for his clinical expertise and for his seminal research on lymph node...

2011-04-12 14:43:36

Current status and future directions explored in issue of Breast Disease The sentinel node (SN) procedure in breast cancer is based on the premise that if the first node into which breast tissue drains is clean, the remaining lymph nodes in the armpit are likely not involved, with no need for removal. This was developed to limit surgical overtreatment and reduce morbidities such as blockage of lymph vessels and shoulder dysfunction. However, in the initial years of the SN procedure, surgeries...

2011-02-24 21:11:23

Validation of a gene expression signature for distinguishing metastasizing from non-metastasizing tumors in head and neck cancers, on a large multi-center cohort The validation of a test, based on gene expression and predicting the tumours that will metastasize in lymph nodes of head & neck cancers, was presented today at the 3rd International Conference on innovative approaches in Head and Neck Oncology (ICHNO), in Barcelona. Dr Robert Takes, from the Radboud University Nijmegen Medical...

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2011-02-09 09:41:14

A study released Tuesday by the Journal of the American Medical Association (JAMA) leaves researchers with evidence that early stage breast cancer patients who have a small amount of lymph node removed fare as well as those who get more extensive surgery, AFP reports. The California-based study included 891 patients who were followed from 1999 to 2004. Researchers studied survival rates among those who had the first lymph node, or sentinel lymph node, removed compared to those who had lymph...

2011-02-09 01:26:19

Among patients with early-stage breast cancer that had spread to a nearby lymph node and who received treatment that included lumpectomy and radiation therapy, women who just had the sentinel lymph node removed (the first lymph node to which cancer is likely to spread from the primary tumor) did not have worse survival than women who had more extensive axillary lymph node dissection (surgery to remove lymph nodes found in the armpit), according to a study in the February 9 issue of JAMA....

2011-02-01 22:11:13

Using "microbubbles" and ultrasound can mean more targeted breast biopsies for patients with early breast cancer, helping to determine treatment and possibly saving those patients from undergoing a second breast cancer surgery, a new study in shows. Patients with early breast cancer undergo a sentinel lymph node biopsy to determine if their cancer has spread, said Dr. Ali Sever, lead author of the study. Ultrasound, on its own, can't distinguish the sentinel lymph node from other lymph nodes,...

2010-04-19 08:29:35

Predicting breast cancer spread from a sentinel lymph node removed during surgery is a hit or miss affair, say researchers: there are still many false negatives, which means the node, when analyzed under a microscope, appears clean of cancer cells, but metastasis can still occur in the patient. The sentinel node is the first lymph node in the axilla that cancer spreads to. Now, researchers from Georgetown Lombardi Comprehensive Center say that they have clues to molecular markers on breast...

2010-02-28 09:00:00

Metastases that were 2 millimeters or less in diameter ("micrometastases") in axillary lymph nodes detected on examination of a single section of the lymph nodes were associated with poorer disease-free and overall survival in breast cancer patients, according to a new study published online February 26 in the Journal of the National Cancer Institute. The prognostic relevance of isolated tumor cells and micrometastases in lymph nodes in breast cancer patients has become a major issue since...


Word of the Day
out-herod
  • In the phrase to out-herod Herod, to be more violent than Herod (as represented in the old mystery plays); hence, to exceed in any excess of evil.
Herod refers to 'Herod the Great,' a Roman client king and 'a madman who murdered his own family and a great many rabbis.' According to the OED, the term is 'chiefly with allusion to Shakespeare's use' in Hamlet.
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