Latest Serotonergic Stories

2013-02-06 10:04:30

-Alcohol dependent (AD) individuals have reduced central serotonergic neurotransmission. -Childhood maltreatment can also have a negative impact on central serotonergic neurotransmission. -A new study has found that self-reported childhood emotional abuse is associated with a 90-percent reduction in central serotonergic neurotransmission in male AD individuals. Individuals who drink excessively or are alcohol dependent (AD) have reduced central serotonergic neurotransmission, which can...

2011-07-28 23:30:28

New insights may be relevant to sudden infant death syndrome Researchers have developed a toolkit that enables them to turn off targeted cell populations while leaving others unaffected. Led by Susan Dymecki, a professor of genetics at Harvard Medical School, the group focused on serotonin-producing neurons, observing how mice behave in a normal environment when suddenly their serotonin neurons are turned down. While their findings affirm earlier studies, the researchers used a technique that...

2011-03-24 07:20:00

Chinese scientists say they have found a chemical inside the brains of mice that controls sexual preference. The researchers, reporting their findings in the journal Nature, said male mice bred without serotonin lose their preference for females. They said it is the first time that a neurotransmitter has been shown to play a role in sexual preference in mammals. The team first bred male mice whose brains were not receptive to serotonin. Experiments showed that these mice had lost preference...

2010-09-16 20:56:25

The response time to antidepressants, such as Prozac, is around three weeks. How can we explain this? The adaptation mechanisms of the neurons to antidepressants has, until now, remained enigmatic. Research, published this week by the teams of Odile Kellermann (Inserm Unit 747 Cellules souches, Signalisation et Prions, Universit© Paris-Descartes) and of Jean-Marie Launay (Inserm Unit 942 Hôpital Lariboisire, Paris and the mental health network, Sant© Mentale),...

2010-01-14 12:47:54

A new study provides insight into the molecular characteristics that make a brain susceptible to anxiety and depression and less likely to respond to treatment with antidepressant medication. The research, published by Cell Press in the January 14th issue of the journal Neuron, may lead to more effective strategies for treating depression, a major health concern throughout the world. Although brain mechanisms associated with depression and anxiety are not completely clear, recent research has...

2008-11-21 08:07:47

DNA plays a role in the amount of alcohol you drink, researchers say. Among alcohol-dependent (AD) individuals, DNA variations in the brain's serotonergic system influence drinking intensity. Specifically the serotonin transporter gene (SLC6A4) contributes to a person's inclination to drink. Researchers analyzed the associations between 275 AD patients seeking treatment and six variations of SLC6A4. Of the six variations, those who carried two T alleles were found to drink more intensely than...

2008-02-13 14:05:00

A new thesis from the Swedish medical university Karolinska Institutet shows that the brain's serotonin system differs between men and women. The scientists who conducted the study think that they have found one of the reasons why depression and chronic anxiety are more common in women than in men. Serotonin is a brain neurotransmitter that is critical to the development and treatment of depression and chronic anxiety, conditions that, for reasons still unknown, are much more common in women...

Word of the Day
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'